(Q46818741)

25 December 2017

title

MyD88 signaling in brain endothelial cells is essential for the neuronal activity and glucocorticoid release during systemic inflammation (English)

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25 December 2017

author name string

D Gosselin

series ordinal

1

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25 December 2017

S Rivest

series ordinal

2

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25 December 2017

language of work or name

English

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publication date

8 January 2008

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25 December 2017

published in

Molecular Psychiatry

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25 December 2017

volume

13

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25 December 2017

issue

5

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25 December 2017

page(s)

480-497

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25 December 2017

How circulating cytokines trigger the neural circuits that control the hypothalamic-pituitary-adrenal axis

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Is survival possible without arachidonate metabolites in the brain during systemic infection?

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An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia

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Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappaB alpha within specific cellular populations of the rat brain

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7 January 2021

Involvement of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes

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7 January 2021

Transcriptional role of the nuclear factor kappa B site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells

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7 January 2021

Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells

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7 January 2021

Basal expression of cyclooxygenase-2 and nuclear factor-interleukin 6 are dominant and coordinately regulated by interleukin 1 in the pancreatic islet

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7 January 2021

Recent advances in molecular biology and physiology of the prostaglandin E2-biosynthetic pathway

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7 January 2021

Cyclooxygenase 2 (COX-2) inhibition increases the inflammatory response in the brain during systemic immune stimuli

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7 January 2021

Inhibitory action of nitric oxide on circulating tumor necrosis factor-induced NF-kappaB activity and COX-2 transcription in the endothelium of the brain capillaries

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7 January 2021

Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: a possible site of prostaglandin synthesis responsible for fever

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7 January 2021

Induction of cyclooxygenase-2 in the brain by cytokines

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7 January 2021

Cyclooxygenase-2 is induced in brain blood vessels during fever evoked by peripheral or central administration of tumor necrosis factor

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7 January 2021

Lipopolysaccharide injected into the cerebral ventricle evokes fever through induction of cyclooxygenase-2 in brain endothelial cells.

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7 January 2021

Inflammatory response: pathway across the blood-brain barrier.

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7 January 2021

Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis

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7 January 2021

Electron microscopic evidence for induction of cyclooxygenase-2 in brain endothelial cells

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7 January 2021

Brain endothelial cells express cyclooxygenase-2 during lipopolysaccharide-induced fever: light and electron microscopic immunocytochemical studies.

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7 January 2021

Cyclooxygenase 2 mRNA expression in rat brain after peripheral injection of lipopolysaccharide.

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7 January 2021

What is the cellular source of prostaglandins in the brain in response to systemic inflammation? Facts and controversies

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7 January 2021

Distinct brain vascular cell types manifest inducible cyclooxygenase expression as a function of the strength and nature of immune insults.

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7 January 2021

Signaling the brain in systemic inflammation: the role of perivascular cells

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7 January 2021

Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages

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7 January 2021

Toll-like receptor 4 on nonhematopoietic cells sustains CNS inflammation during endotoxemia, independent of systemic cytokines.

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7 January 2021

Unraveling the molecular details involved in the intimate link between the immune and neuroendocrine systems.

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7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

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7 January 2021

MyD88 is a key mediator of anorexia, but not weight loss, induced by lipopolysaccharide and interleukin-1 beta.

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Bone marrow-derived cells that populate the adult mouse brain preserve their hematopoietic identity.

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7 January 2021

Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Cooperation between toll-like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram-negative and gram-positive bacteria

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Coexpression of microsomal-type prostaglandin E synthase with cyclooxygenase-2 in brain endothelial cells of rats during endotoxin-induced fever.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Evidence for an intramedullary prostaglandin-dependent mechanism in the activation of stress-related neuroendocrine circuitry by intravenous interleukin-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Adrenocorticotropin release induced by intracerebroventricular injection of recombinant human interleukin-1 in rats: possible involvement of prostaglandin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Functional circuitry in the brain of immune-challenged rats: partial involvement of prostaglandins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

ACTH response induced by interleukin-1 is mediated by CRF secretion stimulated by hypothalamic PGE.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

A functional analysis of EP4 receptor-expressing neurons in mediating the action of prostaglandin E2 within specific nuclei of the brain in response to circulating interleukin-1beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

In altering the release of glucocorticoids, ketorolac exacerbates the effects of systemic immune stimuli on expression of proinflammatory genes in the brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Microinjection of prostaglandin E2 and muscimol into the preoptic area in conscious rats: comparison of effects on plasma adrenocorticotrophic hormone (ACTH), body temperature, locomotor activity, and cardiovascular function.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Ventromedial preoptic prostaglandin E2 activates fever-producing autonomic pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Intraventricular infusion of antagonists of IL-1 and TNFα attenuates neurodegeneration induced by the infection of Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

The febrile response to lipopolysaccharide is blocked in cyclooxygenase-2(-/-), but not in cyclooxygenase-1(-/-) mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Expanding the febrigenic role of cyclooxygenase-2 to the previously overlooked responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Cyclooxygenase-2 mediates the febrile response of mice to interleukin-1beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Irradiation does not compromise or exacerbate the innate immune response in the brains of mice that were transplanted with bone marrow stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002122

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4002122

1 reference

25 December 2017

1 reference

25 December 2017