(Q46826656)

25 December 2017

title

Acceleration of the substrate Calpha deprotonation by an analogue of the second substrate palmitoyl-CoA in Serine Palmitoyltransferase (English)

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25 December 2017

author name string

Hiroko Ikushiro

1

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25 December 2017

Shigeru Fujii

2

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25 December 2017

Yuka Shiraiwa

3

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25 December 2017

Hideyuki Hayashi

4

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25 December 2017

language of work or name

English

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publication date

31 December 2007

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25 December 2017

Journal of Biological Chemistry

number of pages

12

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based on heuristic

inferred from page(s)

published in

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25 December 2017

volume

283

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25 December 2017

issue

12

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25 December 2017

page(s)

7542-7553

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25 December 2017

Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism

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1 reference

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Lipid rafts: elusive or illusive?

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Sphingosine-1-phosphate: an enigmatic signalling lipid

21 January 2018

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Sphingolipid long-chain-base auxotrophs of Saccharomyces cerevisiae: genetics, physiology, and a method for their selection

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Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids

21 January 2018

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The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis

21 January 2018

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Sphingolipid synthesis: identification and characterization of mammalian cDNAs encoding the Lcb2 subunit of serine palmitoyltransferase

21 January 2018

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Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis

21 January 2018

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A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis

21 January 2018

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Cloning and initial characterization of a new subunit for mammalian serine-palmitoyltransferase

21 January 2018

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Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?

21 January 2018

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A water-soluble homodimeric serine palmitoyltransferase from Sphingomonas paucimobilis EY2395T strain. Purification, characterization, cloning, and overproduction

21 January 2018

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Bacterial serine palmitoyltransferase: a water-soluble homodimeric prototype of the eukaryotic enzyme

21 January 2018

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Molecular characterization of membrane-associated soluble serine palmitoyltransferases from Sphingobacterium multivorum and Bdellovibrio stolpii

21 January 2018

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The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis

21 January 2018

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Reactions of serine palmitoyltransferase with serine and molecular mechanisms of the actions of serine derivatives as inhibitors

21 January 2018

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On the chemistry and occurrence of sphingolipid long-chain bases

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies

21 January 2018

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Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism

21 January 2018

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Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans.

21 January 2018

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Transient state kinetic investigation of 5-aminolevulinate synthase reaction mechanism

21 January 2018

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Pyridoxal enzymes: mechanistic diversity and uniformity

21 January 2018

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Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations

21 January 2018

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Characterization of the apparent negative co-operativity induced in Escherichia coli aspartate aminotransferase by the replacement of Asp222 with alanine. Evidence for an extremely slow conformational change

21 January 2018

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Conformation and reaction specificity in pyridoxal phosphate enzymes

21 January 2018

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Transient kinetic studies support refinements to the chemical and kinetic mechanisms of aminolevulinate synthase.

21 January 2018

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Lysine-313 of 5-Aminolevulinate Synthase Acts as a General Base during Formation of the Quinonoid Reaction Intermediates†

21 January 2018

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Suicide inhibition of α-oxamine synthases: structures of the covalent adducts of 8-amino-7-oxononanoate synthase with trifluoroalanine

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M706874200

1 reference

25 December 2017

1 reference

25 December 2017