(Q46828653)

25 December 2017

title

Calcium-permeable acid-sensing ion channel is a molecular target of the neurotoxic metal ion lead (English)

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25 December 2017

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Wei Wang

1

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25 December 2017

Bo Duan

2

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25 December 2017

Han Xu

3

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25 December 2017

Lin Xu

4

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25 December 2017

Tian-Le Xu

5

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25 December 2017

language of work or name

English

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publication date

29 November 2005

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25 December 2017

Journal of Biological Chemistry

published in

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25 December 2017

volume

281

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25 December 2017

issue

5

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25 December 2017

page(s)

2497-2505

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25 December 2017

H(+)-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels

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Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels

21 January 2018

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The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1.

21 January 2018

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Dependence of the acid-sensitive ion channel, ASIC1a, on extracellular Ca(2+) ions

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Properties of the proton-evoked currents and their modulation by Ca2+ and Zn2+ in the acutely dissociated hippocampus CA1 neurons

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Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade

21 January 2018

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Identification of the Ca2+ blocking site of acid-sensing ion channel (ASIC) 1: implications for channel gating

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A proton-gated cation channel involved in acid-sensing

21 January 2018

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Characterization of acid-sensing ion channels in dorsal horn neurons of rat spinal cord.

21 January 2018

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Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a

21 January 2018

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Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

21 January 2018

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The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory

21 January 2018

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Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior

21 January 2018

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The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function.

21 January 2018

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Lead neurotoxicity in children: basic mechanisms and clinical correlates

21 January 2018

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Molecular changes in glutamatergic synapses induced by Pb2+: association with deficits of LTP and spatial learning

21 January 2018

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Presynaptic disruption of transmitter release by lead

21 January 2018

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Molecular cloning of a non-inactivating proton-gated Na+ channel specific for sensory neurons

21 January 2018

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Protein kinase C stimulates the acid-sensing ion channel ASIC2a via the PDZ domain-containing protein PICK1.

21 January 2018

1 reference

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ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1

21 January 2018

1 reference

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cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1

21 January 2018

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Regulation and Modulation of pH in the Brain

21 January 2018

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Modulatory effects of acid-sensing ion channels on action potential generation in hippocampal neurons

21 January 2018

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Glutamate receptor function in learning and memory

21 January 2018

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21 January 2018

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Developmental lead exposure causes spatial learning deficits in adult rats.

21 January 2018

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N-methyl-D-aspartate receptor subunit changes are associated with lead-induced deficits of long-term potentiation and spatial learning.

21 January 2018

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Chronic developmental lead exposure increases the threshold for long-term potentiation in rat dentate gyrus in vivo.

21 January 2018

1 reference

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Age-dependent effects of developmental lead exposure on performance in the Morris water maze.

21 January 2018

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507123200

Analysis of differential effects of Pb2+ on protein kinase C isozymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507123200

Spectroscopic and functional determination of the interaction of Pb2+ with GATA proteins.

21 January 2018

1 reference

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Severe lead poisoning in the plastics industry: a report of three cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507123200

Picomolar concentrations of lead stimulate brain protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507123200

21 January 2018

Identifiers

DOI

10.1074/JBC.M507123200

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25 December 2017

PubMed ID

16319075

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25 December 2017