(Q46832187)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160655%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160655%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

0 references

4

1 reference

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31 December 2019

author name string

Joyce J Repa

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160655%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Hao Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160655%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Tamy C Frank-Cannon

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160655%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Stephen D Turley

5

1 reference

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31 December 2019

John M Dietschy

7

1 reference

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31 December 2019

Malú G Tansey

6

1 reference

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31 December 2019

language of work or name

English

0 references

publication date

1 December 2007

1 reference

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31 December 2019

published in

Journal of Neuroscience

1 reference

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31 December 2019

volume

27

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31 December 2019

issue

52

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31 December 2019

page(s)

14470-14480

1 reference

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Neurosteroids: biosynthesis and function of these novel neuromodulators

31 December 2019

cites work

1 reference

12 December 2020

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

1 reference

12 December 2020

Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency

1 reference

12 December 2020

Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation

1 reference

12 December 2020

The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

1 reference

12 December 2020

Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes

1 reference

12 December 2020

Role of LXRs in control of lipogenesis

1 reference

12 December 2020

Cholesterol is sequestered in the brains of mice with Niemann-Pick type C disease but turnover is increased.

1 reference

12 December 2020

Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease

1 reference

12 December 2020

CNS synaptogenesis promoted by glia-derived cholesterol

1 reference

12 December 2020

Immunocytochemical localization of apolipoprotein D in oligodendrocyte precursor-like cells, perivascular cells, and pericytes in the human cerebral cortex

1 reference

12 December 2020

Regulation of cholesterol homeostasis by the liver X receptors in the central nervous system

1 reference

12 December 2020

Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration

1 reference

12 December 2020

The liver X receptor gene team: potential new players in atherosclerosis

1 reference

12 December 2020

Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes?

1 reference

12 December 2020

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

1 reference

12 December 2020

Patterned Purkinje cell degeneration in mouse models of Niemann-Pick type C disease.

1 reference

12 December 2020

Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover

1 reference

12 December 2020

Fluoro-jade identification of cerebellar granule cell and purkinje cell death in the α1A calcium ion channel mutant mouse, leaner

1 reference

12 December 2020

Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration

1 reference

12 December 2020

Cholesterol homeostasis and function in neurons of the central nervous system

1 reference

12 December 2020

Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse

1 reference

12 December 2020

A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain

1 reference

12 December 2020

Postnatal development of inflammation in a murine model of Niemann-Pick type C disease: immunohistochemical observations of microglia and astroglia

1 reference

12 December 2020

Blood to brain to the rescue.

1 reference

12 December 2020

Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

1 reference

12 December 2020

Molecular diversity of astrocytes with implications for neurological disorders

1 reference

12 December 2020

Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone

1 reference

12 December 2020

Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal

1 reference

12 December 2020

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

1 reference

12 December 2020

Quantitative real-time polymerase chain reaction measurement of regulators of G-protein signaling mRNA levels in mouse tissues

1 reference

12 December 2020

Generation and function of astroglial lipoproteins from Niemann-Pick type C1-deficient mice

1 reference

12 December 2020

Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis

1 reference

12 December 2020

Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption

1 reference

12 December 2020

Cholesterol homeostasis in neurons and glial cells

1 reference

12 December 2020

Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease

1 reference

12 December 2020

The power of real-time PCR.

1 reference

12 December 2020

Cholesterol accumulation and liver cell death in mice with Niemann-Pick type C disease

1 reference

12 December 2020

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

1 reference

12 December 2020

Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease

1 reference

12 December 2020

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

1 reference

12 December 2020

Lysosomal unesterified cholesterol content correlates with liver cell death in murine Niemann-Pick type C disease

1 reference

12 December 2020

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

1 reference

12 December 2020

T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR

1 reference

12 December 2020

Receptor-mediated and bulk-phase endocytosis cause macrophage and cholesterol accumulation in Niemann-Pick C disease

1 reference

12 December 2020

Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors

1 reference

12 December 2020

Systematic gene expression mapping clusters nuclear receptors according to their function in the brain.

1 reference

12 December 2020

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

1 reference

12 December 2020

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

1 reference

12 December 2020

A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol

1 reference

12 December 2020

Role of lipoproteins in the delivery of lipids to axons during axonal regeneration

1 reference

12 December 2020

Cellular cholesterol storage in the Niemann-Pick disease type C mouse is associated with increased expression and defective processing of apolipoprotein D.

1 reference

12 December 2020

Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation

1 reference

12 December 2020

Cholesterol balance and metabolism in mice with loss of function of Niemann-Pick C protein.

1 reference

12 December 2020

10.1523/JNEUROSCI.4823-07.2007

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160655%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160655%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

PubMed publication ID

18160655

1 reference