(Q46850323)

25 December 2017

title

Mouse Tcf3 represses canonical Wnt signaling by either competing for β-catenin binding or through occupation of DNA-binding sites (English)

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25 December 2017

author name string

Nina Solberg

1

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25 December 2017

Ondrej Machon

2

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25 December 2017

Olga Machonova

3

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25 December 2017

Stefan Krauss

4

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25 December 2017

publication date

22 January 2012

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25 December 2017

Molecular and Cellular Biochemistry

published in

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25 December 2017

volume

365

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25 December 2017

issue

1-2

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25 December 2017

page(s)

53-63

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25 December 2017

https://scigraph.springernature.com/pub.10.1007/s11010-012-1243-9

exact match

0 references

cites work

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Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal

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Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells

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Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal

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Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewal

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T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways

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Repressor activity of Headless/Tcf3 is essential for vertebrate head formation.

21 January 2018

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Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.

21 January 2018

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Tcf3 governs stem cell features and represses cell fate determination in skin

21 January 2018

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Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

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An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

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The mouse enhancer element D6 directs Cre recombinase activity in the neocortex and the hippocampus.

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Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

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Forebrain-specific promoter/enhancer D6 derived from the mouse Dach1 gene controls expression in neural stem cells

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Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

21 January 2018

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Crystal structure of a beta-catenin/Tcf complex

21 January 2018

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Structural basis for DNA bending by the architectural transcription factor LEF-1

21 January 2018

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A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus.

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Tcf3: a transcriptional regulator of axis induction in the early embryo

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The transcriptional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobin

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Role of beta-catenin in the developing cortical and hippocampal neuroepithelium

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Repression of organizer genes in dorsal and ventral Xenopus cells mediated by maternal XTcf3.

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12 December 2020

Functional diversity of Xenopus lymphoid enhancer factor/T-cell factor transcription factors relies on combinations of activating and repressing elements

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12 December 2020

Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool

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12 December 2020

From cortical rotation to organizer gene expression: toward a molecular explanation of axis specification in Xenopus

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12 December 2020

A local Wnt-3a signal is required for development of the mammalian hippocampus

1 reference

12 December 2020

10.1007/S11010-012-1243-9

Identifiers

DOI

1 reference

25 December 2017

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25 December 2017