(Q46850551)

25 December 2017

title

Targeting lipid metabolism by the lipoprotein lipase inhibitor orlistat results in apoptosis of B-cell chronic lymphocytic leukemia cells (English)

1 reference

25 December 2017

triacylglycerol lipase inhibitor

0 references

1 reference

1 reference

1 reference

B-cell chronic lymphocytic leukemia

inferred from title

1 reference

inferred from title

author

Christian P. Pallasch

1

1 reference

25 December 2017

Joachim Schultze

7

1 reference

25 December 2017

author name string

Schwamb J

2

1 reference

25 December 2017

Königs S

3

1 reference

25 December 2017

Schulz A

4

1 reference

25 December 2017

Debey S

5

1 reference

25 December 2017

Kofler D

6

1 reference

25 December 2017

Hallek M

8

1 reference

25 December 2017

Ultsch A

9

1 reference

25 December 2017

Wendtner CM

10

1 reference

25 December 2017

publication date

13 December 2007

1 reference

25 December 2017

published in

Leukemia

1 reference

25 December 2017

volume

22

1 reference

25 December 2017

page(s)

585-592

1 reference

25 December 2017

issue

3

1 reference

25 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2405058

exact match

0 references

cites work

Chronic B cell malignancies and bone marrow microenvironment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Chronic lymphocytic leukemia: revelations from the B-cell receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Interactions of lipoprotein lipase with the active-site inhibitor tetrahydrolipstatin (Orlistat).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Routine analysis of IgVH mutational status in CLL patients using BIOMED-2 standardized primers and protocols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Engagement of the B-cell antigen receptor (BCR) allows efficient transduction of ZAP-70-positive primary B-CLL cells by recombinant adeno-associated virus (rAAV) vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

A highly standardized, robust, and cost-effective method for genome-wide transcriptome analysis of peripheral blood applicable to large-scale clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

A novel calcium-independent phospholipase A2, cPLA2-gamma, that is prenylated and contains homology to cPLA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Arachidonate release and eicosanoid generation by group IIE phospholipase A(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Cellular arachidonate-releasing function and inflammation-associated expression of group IIF secretory phospholipase A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Differentially expressed late constituents of the epidermal cornified envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

PATE, a gene expressed in prostate cancer, normal prostate, and testis, identified by a functional genomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Mitogenic signalling by B2 bradykinin receptor in epithelial breast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Overexpression of phospholipase D prevents actinomycin D-induced apoptosis through potentiation of phosphoinositide 3-kinase signalling pathways in Chinese-hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Phospholipase D2 acts as an essential adaptor protein in the activation of Syk in antigen-stimulated mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Gene ontology: tool for the unification of biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Cytoplasmic phospholipase A2 levels correlate with apoptosis in human colon tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Human group IVC phospholipase A2 (cPLA2gamma). Roles in the membrane remodeling and activation induced by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Lipoprotein lipase expression is a novel prognostic factor in B-cell chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Orlistat: a review of its use in the management of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Antitumoral actions of the anti-obesity drug orlistat (XenicalTM) in breast cancer cells: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Fludarabine in combination with alemtuzumab is effective and feasible in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: results of a phase II trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Advances in chemotherapy for chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

Review of limited systemic absorption of orlistat, a lipase inhibitor, in healthy human volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

The LPL/ADAM29 expression ratio is a novel prognosis indicator in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

High expression of lipoprotein lipase in poor risk B-cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

B-cell chronic lymphocytic leukemia: a bird of a different feather

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

7 January 2021

In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

7 January 2021

Deregulated expression of fat and muscle genes in B-cell chronic lymphocytic leukemia with high lipoprotein lipase expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

7 January 2021

Diacylglycerols derived from membrane phospholipids are metabolized by lipases in A10 smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

7 January 2021

The effect of orlistat and fenofibrate, alone or in combination, on small dense LDL and lipoprotein-associated phospholipase A2 in obese patients with metabolic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405058

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2405058

1 reference

25 December 2017

PubMed ID

18079738

1 reference

25 December 2017