(Q46858649)

25 December 2017

title

Targeted activation of c-Jun N-terminal kinase in vivo induces restrictive cardiomyopathy and conduction defects (English)

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25 December 2017

restrictive cardiomyopathy

main subject

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7

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25 December 2017

author name string

Brian G Petrich

1

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25 December 2017

Benjamin C Eloff

2

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25 December 2017

Deborah L Lerner

3

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25 December 2017

Attila Kovacs

4

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25 December 2017

Jeffrey E Saffitz

5

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25 December 2017

David S Rosenbaum

6

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25 December 2017

language of work or name

English

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publication date

23 January 2004

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25 December 2017

Journal of Biological Chemistry

published in

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25 December 2017

volume

279

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25 December 2017

issue

15

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25 December 2017

page(s)

15330-15338

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25 December 2017

Signal transduction by the JNK group of MAP kinases

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21 January 2018

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21 January 2018

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21 January 2018

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c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling

21 January 2018

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c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes

21 January 2018

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Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43

21 January 2018

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The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

21 January 2018

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21 January 2018

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Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7

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Selective requirement of myosin light chain 2v in embryonic heart function

21 January 2018

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A post-transcriptional compensatory pathway in heterozygous ventricular myosin light chain 2-deficient mice results in lack of gene dosage effect during normal cardiac growth or hypertrophy.

21 January 2018

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Transgenic Galphaq overexpression induces cardiac contractile failure in mice

21 January 2018

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RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload

21 January 2018

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21 January 2018

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Activation of the TGF-beta/activin-Smad2 pathway during allergic airway inflammation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Temporal activation of c-Jun N-terminal kinase in adult transgenic heart via cre-loxP-mediated DNA recombination

21 January 2018

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Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice.

21 January 2018

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

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Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress

21 January 2018

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Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis

21 January 2018

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21 January 2018

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Oxidative stress induces DNA fragmentation and caspase activation via the c-Jun NH2-terminal kinase pathway in H9c2 cardiac muscle cells.

21 January 2018

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Increased expression of cytoskeletal, linkage, and extracellular proteins in failing human myocardium

21 January 2018

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Accumulation of fetal fibronectin mRNAs during the development of rat cardiac hypertrophy induced by pressure overload

21 January 2018

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Fibrosis, matrix metalloproteinases, and inflammation in the heart of DOCA-salt hypertensive rats: role of ET(A) receptors

21 January 2018

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Myocardial fibrosis in chronic aortic regurgitation: molecular and cellular responses to volume overload

21 January 2018

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Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension

21 January 2018

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The TGF beta superfamily in myocardium: ligands, receptors, transduction, and function

21 January 2018

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Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions

21 January 2018

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

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Fibrosis and hypertensive heart disease

21 January 2018

1 reference

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Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex

21 January 2018

1 reference

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Localization of sodium channels in intercalated disks modulates cardiac conduction

21 January 2018

1 reference

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Electrophysiological remodeling in hypertrophy and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314142200

Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314142200

21 January 2018

Identifiers

DOI

10.1074/JBC.M314142200

1 reference

25 December 2017

PubMed ID

14742426

1 reference

25 December 2017