(Q46863352)

25 December 2017

title

Effects of a leukemia-associated gain-of-function mutation of SHP-2 phosphatase on interleukin-3 signaling (English)

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25 December 2017

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Wen-Mei Yu

1

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25 December 2017

Hanako Daino

2

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25 December 2017

Jing Chen

3

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25 December 2017

Kevin D Bunting

4

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25 December 2017

Cheng-Kui Qu

5

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25 December 2017

language of work or name

English

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publication date

21 December 2005

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25 December 2017

Journal of Biological Chemistry

published in

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25 December 2017

volume

281

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25 December 2017

issue

9

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25 December 2017

page(s)

5426-5434

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25 December 2017

Juvenile myelomonocytic leukemia: molecular understanding and prospects for therapy

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Nf1 and Gmcsf interact in myeloid leukemogenesis

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Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines

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IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled

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Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor

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Shc associates with the IL-3 receptor β subunit, SHIP and Gab2 following IL-3 stimulation

21 January 2018

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New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

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Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

21 January 2018

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Jak2 is essential for signaling through a variety of cytokine receptors

21 January 2018

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The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

21 January 2018

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Combinatorial control of the specificity of protein tyrosine phosphatases

21 January 2018

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Role of the SHP-2 tyrosine phosphatase in cytokine-induced signaling and cellular response

21 January 2018

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A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development

21 January 2018

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Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells

21 January 2018

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Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development

21 January 2018

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Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling

21 January 2018

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A negative role of SHP-2 tyrosine phosphatase in growth factor-dependent hematopoietic cell survival

21 January 2018

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Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

21 January 2018

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Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

21 January 2018

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Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

21 January 2018

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Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

21 January 2018

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Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation

21 January 2018

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Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

21 January 2018

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Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.

21 January 2018

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Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor

21 January 2018

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Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507622200

Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507622200

Crystal structure of the tyrosine phosphatase SHP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507622200

Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507622200

21 January 2018

Identifiers

DOI

10.1074/JBC.M507622200

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25 December 2017

1 reference

25 December 2017