(Q46865333)

English

Three-dimensional quantitative structure-activity relationship (3D QSAR) and pharmacophore elucidation of tetrahydropyran derivatives as serotonin and norepinephrine transporter inhibitors.

scientific article published on 4 December 2007

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Three-dimensional quantitative structure-activity relationship (3D QSAR) and pharmacophore elucidation of tetrahydropyran derivatives as serotonin and norepinephrine transporter inhibitors (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

0 references

quantitative structure-activity relationship

1 reference

based on heuristic

inferred from title

Prashant S Kharkar

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Maarten E A Reith

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

publication date

4 December 2007

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Journal of Computer - Aided Molecular Design

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

22

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1-17

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PET studies of brain monoamine transporters.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The selective norepinephrine reuptake inhibitor antidepressant reboxetine: pharmacological and clinical profile.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic and computer-assisted analysis of the structural requirements for selective, high-affinity ligand binding to diazepam-insensitive benzodiazepine receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of effects of dual transporter inhibitors on monoamine transporters and extracellular levels in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonergic dysfunction, negative mood states, and response to alcohol

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine transporter as target for drug development of cocaine dependence medications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of mood disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Affinity and selectivity of matrix metalloproteinase inhibitors: a chemometrical study from the perspective of ligands and proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional quantitative structure-activity relationship analyses using comparative molecular field analysis and comparative molecular similarity indices analysis to elucidate selectivity differences of inhibitors binding to trypsin, thrombin,

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reboxetine: functional inhibition of monoamine transporters and nicotinic acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced levels of norepinephrine transporters in the locus coeruleus in major depression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reboxetine: a selective norepinephrine reuptake inhibitor for the treatment of depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural requirements for 2,4- and 3,6-disubstituted pyran biomimetics of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine compounds to interact with monoamine transporters.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single nucleotide polymorphisms distinguish multiple dopamine transporter alleles in primates: implications for association with attention deficit hyperactivity disorder and other neuropsychiatric disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MOPAC: a semiempirical molecular orbital program

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinit

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial orthostatic tachycardia due to norepinephrine transporter deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin, dopamine and norepinephrine transporters in the central nervous system and their inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotransmitter transporters: recent progress

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10822-007-9146-7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

DBLP publication ID

journals/jcamd/KharkarRD08

1 reference

DBLP Dataset 2021-01-02

28 January 2021

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18060532%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q46865333&oldid=2208191386"