(Q46875861)

26 December 2017

title

Mechanism of auxiliary β-subunit-mediated membrane targeting of L-type (Ca(V)1.2) channels (English)

1 reference

26 December 2017

author name string

Kun Fang

series ordinal

1

1 reference

26 December 2017

Henry M Colecraft

series ordinal

2

1 reference

26 December 2017

language of work or name

English

0 references

publication date

11 July 2011

1 reference

26 December 2017

published in

Journal of Physiology

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26 December 2017

volume

589

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26 December 2017

issue

Pt 18

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26 December 2017

page(s)

4437-4455

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26 December 2017

Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation

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Direct inhibition of P/Q-type voltage-gated Ca 2+ channels by Gem does not require a direct Gem/Ca v β interaction

7 October 2018

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Molecular determinants of the CaVbeta-induced plasma membrane targeting of the CaV1.2 channel

7 October 2018

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Rem, a member of the RGK GTPases, inhibits recombinant CaV1.2 channels using multiple mechanisms that require distinct conformations of the GTPase

7 October 2018

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Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons

7 October 2018

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How do ER export motifs work on ion channel trafficking?

7 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation

7 October 2018

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Orientation of the calcium channel beta relative to the alpha(1)2.2 subunit is critical for its regulation of channel activity

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Calcium channel regulation and presynaptic plasticity

7 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Control of K(Ca) channels by calcium nano/microdomains

7 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Alanine-scanning mutagenesis defines a conserved energetic hotspot in the CaValpha1 AID-CaVbeta interaction site that is critical for channel modulation.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Ca2+/calmodulin regulates trafficking of Ca(V)1.2 Ca2+ channels in cultured hippocampal neurons.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Autoinhibitory control of the CaV1.2 channel by its proteolytically processed distal C-terminal domain.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Regulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

The importance of occupancy rather than affinity of CaV(beta) subunits for the calcium channel I-II linker in relation to calcium channel function

7 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Insights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain-Ca2+/calmodulin complex

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Transfer of beta subunit regulation from high to low voltage-gated Ca2+ channels

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Imaging of receptor trafficking by using alpha-bungarotoxin-binding-site-tagged receptors

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Structural basis of the alpha1-beta subunit interaction of voltage-gated Ca2+ channels

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Structure of a complex between a voltage-gated calcium channel beta-subunit and an alpha-subunit domain.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Structural analysis of the voltage-dependent calcium channel beta subunit functional core and its complex with the alpha 1 interaction domain

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Membrane-associated guanylate kinase-like properties of beta-subunits required for modulation of voltage-dependent Ca2+ channels

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Identification of the components controlling inactivation of voltage-gated Ca2+ channels

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Beta subunits of voltage-gated calcium channels

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

The voltage-dependent calcium channel beta subunit contains two stable interacting domains

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Signaling from synapse to nucleus: the logic behind the mechanisms

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

FRET two-hybrid mapping reveals function and location of L-type Ca2+ channel CaM preassociation.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Cardiac excitation-contraction coupling

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

The interaction between the I-II loop and the III-IV loop of Cav2.1 contributes to voltage-dependent inactivation in a beta -dependent manner.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Preassociation of calmodulin with voltage-gated Ca(2+) channels revealed by FRET in single living cells

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Evidence for two concentration-dependent processes for beta-subunit effects on alpha1B calcium channels

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Molecular basis of calmodulin tethering and Ca2+-dependent inactivation of L-type Ca2+ channels

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Role of ER export signals in controlling surface potassium channel numbers

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Ca(2+) sensors of L-type Ca(2+) channel

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

The [beta]2a subunit is a molecular groom for the Ca2+ channel inactivation gate.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Role of the C terminus of the alpha 1C (CaV1.2) subunit in membrane targeting of cardiac L-type calcium channels

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

The I-II loop of the Ca2+ channel alpha1 subunit contains an endoplasmic reticulum retention signal antagonized by the beta subunit.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Calmodulin supports both inactivation and facilitation of L-type calcium channels.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Ca2+/calmodulin binds to and modulates P/Q-type calcium channels

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Complexes of the alpha1C and beta subunits generate the necessary signal for membrane targeting of class C L-type calcium channels

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Molecular characterization of a neuronal low-voltage-activated T-type calcium channel

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Mutation of the Ca2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Absence of the beta subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the alpha 1 subunit and eliminates excitation-contraction coupling

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Potentiation by the beta subunit of the ratio of the ionic current to the charge movement in the cardiac calcium channel.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Subunit regulation of the neuronal alpha 1A Ca2+ channel expressed in Xenopus oocytes.

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Modification of Ca2+ channel activity by deletions at the carboxyl terminus of the cardiac alpha 1 subunit

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel

7 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208217

Reporting ethical matters in the Journal of Physiology: standards and advice

7 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.214247

Calcium channel β-subunit binds to a conserved motif in the I–II cytoplasmic linker of the α1-subunit

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.214247

The Cavβ subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21746784

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Calmodulin is the Ca2+ sensor for Ca2+ -dependent inactivation of L-type calcium channels

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21746784

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multiple determinants in voltage-dependent P/Q calcium channels control their retention in the endoplasmic reticulum

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21746784

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1113/JPHYSIOL.2011.214247

1 reference

26 December 2017

PMC publication ID

3208217

0 references

1 reference

26 December 2017