(Q46881459)

26 December 2017

title

Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3,4,5-(PO4)3 in muscle of diabetic subjects (English)

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26 December 2017

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V Luna

1

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26 December 2017

L Casauban

2

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26 December 2017

M P Sajan

3

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26 December 2017

J Gomez-Daspet

4

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26 December 2017

J L Powe

5

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26 December 2017

A Miura

6

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26 December 2017

J Rivas

7

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26 December 2017

M L Standaert

8

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26 December 2017

R V Farese

9

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26 December 2017

publication date

5 January 2006

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26 December 2017

published in

Diabetologia

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26 December 2017

volume

49

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26 December 2017

issue

2

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26 December 2017

page(s)

375-382

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26 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-005-0112-4

exact match

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cites work

Metformin increases insulin sensitivity and basal glucose clearance in Type 2 (non-insulin dependent) diabetes mellitus

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-005-0112-4

Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-005-0112-4

Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-005-0112-4

PKC-zeta mediates insulin effects on glucose transport in cultured preadipocyte-derived human adipocytes

21 January 2018

1 reference

12 December 2020

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

1 reference

12 December 2020

Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport

1 reference

12 December 2020

Defective Activation of Protein Kinase C-z in Muscle by Insulin and Phosphatidylinositol-3,4,5,-(PO(4))(3) in Obesity and Polycystic Ovary Syndrome

1 reference

12 December 2020

Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells

1 reference

12 December 2020

Effect of metformin on peripheral insulin sensitivity in non insulin dependent diabetes mellitus.

1 reference

12 December 2020

Combined metformin-sulfonylurea treatment of patients with noninsulin-dependent diabetes in fair to poor glycemic control

1 reference

12 December 2020

Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota

1 reference

12 December 2020

Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus.

1 reference

12 December 2020

Troglitazone but not metformin restores insulin-stimulated phosphoinositide 3-kinase activity and increases p110beta protein levels in skeletal muscle of type 2 diabetic subjects

1 reference

12 December 2020

Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction

1 reference

12 December 2020

In vivo adenoviral delivery of recombinant human protein kinase C-zeta stimulates glucose transport activity in rat skeletal muscle

1 reference

12 December 2020

Role of AMP-activated protein kinase in mechanism of metformin action

1 reference

12 December 2020

Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes

1 reference

12 December 2020

Insulin activates protein kinases C-zeta and C-lambda by an autophosphorylation-dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes.

1 reference

12 December 2020

Metformin improves peripheral but not hepatic insulin action in obese patients with type II diabetes.

1 reference

12 December 2020

Acute antihyperglycemic mechanisms of metformin in NIDDM. Evidence for suppression of lipid oxidation and hepatic glucose production

1 reference

12 December 2020

Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes

1 reference

12 December 2020

Isoform-specific and exercise intensity-dependent activation of 5'-AMP-activated protein kinase in human skeletal muscle

1 reference

12 December 2020

Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high

1 reference

12 December 2020

Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects.

1 reference

12 December 2020

Metformin treatment enhances insulin-stimulated glucose transport in skeletal muscle of Sprague-Dawley rats

1 reference

12 December 2020

Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport

1 reference

12 December 2020

Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylinositol-3' kinase activation, and impaired atypical protein kinase C (zeta/lambda) activation in myotubes from obese patients with impaired glucose tolerance

1 reference

12 December 2020

Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise

1 reference

12 December 2020

Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport

1 reference

12 December 2020

PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity

1 reference

12 December 2020

Metformin, but not exercise training, increases insulin responsiveness in skeletal muscle of Sprague-Dawley rats

1 reference

12 December 2020

Tissue-specific differences in activation of atypical protein kinase C and protein kinase B in muscle, liver, and adipocytes of insulin receptor substrate-1 knockout mice

1 reference

12 December 2020

Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-lambda on insulin-stimulated glucose transport in L6 myotubes

1 reference

12 December 2020

Glucose transport in human skeletal muscle cells in culture. Stimulation by insulin and metformin

1 reference

12 December 2020

Impaired activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 in cultured preadipocyte-derived adipocytes and myotubes of obese subjects

1 reference

12 December 2020

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

1 reference

12 December 2020

Defective activation of atypical protein kinase C zeta and lambda by insulin and phosphatidylinositol-3,4,5-(PO4)(3) in skeletal muscle of rats following high-fat feeding and streptozotocin-induced diabetes

1 reference

12 December 2020

10.1007/S00125-005-0112-4

Identifiers

DOI

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26 December 2017

PubMed ID

16395615

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26 December 2017