(Q46883020)

26 December 2017

title

Caspase-dependent and -independent cell death of Jurkat human leukemia cells induced by novel synthetic ceramide analogs (English)

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26 December 2017

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5

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26 December 2017

author name string

Granot T

1

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26 December 2017

Milhas D

2

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26 December 2017

Carpentier S

3

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26 December 2017

Dagan A

4

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26 December 2017

Gatt S

6

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26 December 2017

Levade T

7

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26 December 2017

publication date

1 March 2006

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26 December 2017

published in

Leukemia

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26 December 2017

volume

20

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26 December 2017

issue

3

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26 December 2017

page(s)

392-399

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26 December 2017

Biologically active sphingolipids in cancer pathogenesis and treatment

cites work

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Targeting ceramide metabolism--a strategy for overcoming drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Sphingolipid metabolism enzymes as targets for anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

N-acylated serinol is a novel ceramide mimic inducing apoptosis in neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT(388)-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Ceramide promotes the death of human cervical tumor cells in the absence of biochemical and morphological markers of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

The ceramide analog, B13, induces apoptosis in prostate cancer cell lines and inhibits tumor growth in prostate cancer xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Novel ceramide analogs as potential chemotherapeutic agents in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Positively charged ceramide is a potent inducer of mitochondrial permeabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Synthetic, non-natural sphingolipid analogs inhibit the biosynthesis of cellular sphingolipids, elevate ceramide and induce apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Caspase-10 triggers Bid cleavage and caspase cascade activation in FasL-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Involvement of FAN in TNF-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Determination of ceramides and diglycerides by the diglyceride kinase assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Simultaneous quantitative analysis of ceramide and sphingosine in mouse blood by naphthalene-2,3-dicarboxyaldehyde derivatization after hydrolysis with ceramidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

The therapeutic potential of modulating the ceramide/sphingomyelin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Ceramides induce a form of apoptosis in human acute lymphoblastic leukemia cells that is inhibited by Bcl-2, but not by CrmA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Bcl-2 antagonizes apoptotic cell death induced by two new ceramide analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Synthesis and characterization of novel ceramide analogs for induction of apoptosis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Ceramide analogues in apoptosis: a new strategy for anticancer drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Akt protein kinase inhibits non-apoptotic programmed cell death induced by ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Ceramide induces caspase-dependent and -independent apoptosis in A-431 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line. Role for endogenous ceramide in mediating the action of exogenous ceramide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Sphingomyelin synthase as a potential target for D609-induced apoptosis in U937 human monocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Fenretinide cytotoxicity for Ewing's sarcoma and primitive neuroectodermal tumor cell lines is decreased by hypoxia and synergistically enhanced by ceramide modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

Programmed cell death induced by ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

7 January 2021

Stereospecific induction of apoptosis in U937 cells by N-octanoyl-sphingosine stereoisomers and N-octyl-sphingosine. The ceramide amide group is not required for apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

7 January 2021

Ceramide-induced apoptosis occurs independently of caspases and is decreased by leupeptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

7 January 2021

Positive feedback control of neutral sphingomyelinase activity by ceramide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404084

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2404084

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26 December 2017

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26 December 2017