(Q46909899)

26 December 2017

title

A pathway of structural changes produced by monastrol binding to Eg5. (English)

1 reference

26 December 2017

author name string

Zoltan Maliga

1

1 reference

26 December 2017

Jun Xing

2

1 reference

26 December 2017

Herbert Cheung

3

1 reference

26 December 2017

Laura J Juszczak

4

1 reference

26 December 2017

Joel M Friedman

5

1 reference

26 December 2017

Steven S Rosenfeld

6

1 reference

26 December 2017

language of work or name

English

0 references

publication date

23 January 2006

1 reference

26 December 2017

Journal of Biological Chemistry

published in

1 reference

26 December 2017

volume

281

1 reference

26 December 2017

page(s)

7977-7982

1 reference

26 December 2017

issue

12

1 reference

26 December 2017

The road less traveled: emerging principles of kinesin motor utilization

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

21 January 2018

Intraflagellar Transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Kinesin: world's tiniest biped

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Microtubule-depolymerizing kinesins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Antitumor activity of a kinesin inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Monastrol inhibition of the mitotic kinesin Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Interaction of the mitotic inhibitor monastrol with human kinesin Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Inhibition of a mitotic motor protein: where, how, and conformational consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Docking and rolling, a model of how the mitotic motor Eg5 works

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Proximity relationships and structural dynamics of the phalloidin binding site of actin filaments in solution and on single actin filaments on heavy meromyosin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Switch-based mechanism of kinesin motors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

A structural change in the kinesin motor protein that drives motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

On the wobbling-in-cone analysis of fluorescence anisotropy decay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Mechanism of inhibition of human KSP by monastrol: insights from kinetic analysis and the effect of ionic strength on KSP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511955200

21 January 2018

Identifiers

DOI

10.1074/JBC.M511955200

1 reference

26 December 2017

PubMed ID

16434397

1 reference

26 December 2017