(Q46915466)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Inhibition of Akt/mTOR attenuates age-related changes in mesenchymal stem cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

main subject

mesenchymal stem cell

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

Borzo Gharibi

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Samira Farzadi

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Francis J Hughes

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

publication date

1 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

2256-2266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

Aging and replicative senescence have related effects on human stem and progenitor cells

21 January 2018

1 reference

Increasing donor age adversely impacts beneficial effects of bone marrow but not smooth muscle myocardial cell therapy

21 January 2018

1 reference

Aging of marrow stromal (skeletal) stem cells and their contribution to age-related bone loss

21 January 2018

1 reference

Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice.

21 January 2018

1 reference

Effects of medium supplements on proliferation, differentiation potential, and in vitro expansion of mesenchymal stem cells

21 January 2018

1 reference

Different facets of aging in human mesenchymal stem cells

21 January 2018

1 reference

21 January 2018

1 reference

A link between the accumulation of DNA damage and loss of multi-potency of human mesenchymal stromal cells

21 January 2018

1 reference

Atmospheric oxygen inhibits growth and differentiation of marrow-derived mouse mesenchymal stem cells via a p53-dependent mechanism: implications for long-term culture expansion

21 January 2018

1 reference

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

21 January 2018

1 reference

The aged niche disrupts muscle stem cell quiescence.

21 January 2018

1 reference

mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.

21 January 2018

1 reference

mTORC1 signaling governs hematopoietic stem cell quiescence

21 January 2018

1 reference

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells

21 January 2018

1 reference

mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion.

21 January 2018

1 reference

An emerging role for TOR signaling in mammalian tissue and stem cell physiology

21 January 2018

1 reference

mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells

21 January 2018

1 reference

Akt- and Erk-mediated regulation of proliferation and differentiation during PDGFRβ-induced MSC self-renewal

21 January 2018

1 reference

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

21 January 2018

1 reference

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

21 January 2018

1 reference

Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

21 January 2018

1 reference

Hypoxia signalling through mTOR and the unfolded protein response in cancer

21 January 2018

1 reference

A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche

21 January 2018

1 reference

Adenosine receptor subtype expression and activation influence the differentiation of mesenchymal stem cells to osteoblasts and adipocytes

21 January 2018

1 reference

Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways

21 January 2018

1 reference

Bone and fat connection in aging bone

21 January 2018

1 reference

Senescence-associated intrinsic mechanisms of osteoblast dysfunctions.

21 January 2018

1 reference

Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through down-regulation of E2A-p21 by HIF-TWIST.

21 January 2018

1 reference

Oct4 and Nanog directly regulate Dnmt1 to maintain self-renewal and undifferentiated state in mesenchymal stem cells.

21 January 2018

1 reference

How to track cellular aging of mesenchymal stromal cells?

21 January 2018

1 reference

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines

21 January 2018

1 reference

Mechanisms that regulate stem cell aging and life span

21 January 2018

1 reference

mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis.

21 January 2018

1 reference

Plzf Regulates Germline Progenitor Self-Renewal by Opposing mTORC1

21 January 2018

1 reference

The key regulatory roles of the PI3K/Akt signaling pathway in the functionalities of mesenchymal stem cells and applications in tissue regeneration

21 January 2018

1 reference

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

21 January 2018

1 reference

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

21 January 2018

1 reference

Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner

21 January 2018

1 reference

Abrogation of MAPK and Akt signaling by AEE788 synergistically potentiates histone deacetylase inhibitor-induced apoptosis through reactive oxygen species generation

21 January 2018

1 reference

Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading.

21 January 2018

1 reference

Reactive oxygen species on bone mineral density and mechanics in Cu,Zn superoxide dismutase (Sod1) knockout mice

21 January 2018

1 reference

Nanog reverses the effects of organismal aging on mesenchymal stem cell proliferation and myogenic differentiation potential

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/STEM.1709

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659476%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference