(Q46919881)

26 December 2017

title

A post-transcriptional process contributes to efficient gamma-globin gene silencing in definitive erythroid cells (English)

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26 December 2017

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J Eric Russell

1

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26 December 2017

publication date

1 November 2007

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26 December 2017

European Journal of Haematology

published in

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26 December 2017

volume

79

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26 December 2017

issue

6

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26 December 2017

page(s)

516-525

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26 December 2017

Regulation of human fetal hemoglobin: new players, new complexities

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Persistent gamma-globin expression in adult transgenic mice is mediated by HPFH-2, HPFH-3, and HPFH-6 breakpoint sequences.

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The Corfu deltabeta thalassemia deletion disrupts gamma-globin gene silencing and reveals post-transcriptional regulation of HbF expression

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beta 0 thalassemia, a nonsense mutation in man

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Processing of human beta-globin mRNA precursor to mRNA is defective in three patients with beta+-thalassemia

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Developmental silencing of the embryonic zeta-globin gene: concerted action of the promoter and the 3'-flanking region combined with stage-specific silencing by the transcribed segment

21 January 2018

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Reselution of hemoglobin subunits by electrophoresis in acid urea polyacrylamide gels containing Triton X-100

21 January 2018

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Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy

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Sequence divergence in the 3' untranslated regions of human zeta- and alpha-globin mRNAs mediates a difference in their stabilities and contributes to efficient alpha-to-zeta gene development switching

21 January 2018

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A 3'UTR mutation affects beta-globin expression without altering the stability of its fully processed mRNA.

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Dynamic posttranscriptional regulation of epsilon-globin gene expression in vivo

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Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase.

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A dominant control region from the human beta-globin locus conferring integration site-independent gene expression

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Erythroid cell-specific determinants of alpha-globin mRNA stability

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Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3' nontranslated region

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Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability

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An mRNA stability complex functions with poly(A)-binding protein to stabilize mRNA in vitro

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The poly(A)-binding protein and an mRNA stability protein jointly regulate an endoribonuclease activity

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The KH-domain protein alpha CP has a direct role in mRNA stabilization independent of its cognate binding site

21 January 2018

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Assembly of the alpha-globin mRNA stability complex reflects binary interaction between the pyrimidine-rich 3' untranslated region determinant and poly(C) binding protein alphaCP

21 January 2018

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A nucleolin-binding 3' untranslated region element stabilizes beta-globin mRNA in vivo

21 January 2018

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Chromatin structure and developmental expression of the human alpha-globin cluster

21 January 2018

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Embryonic and fetal globins are expressed in adult erythroid progenitor cells and in erythroid cell cultures

21 January 2018

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Dissecting the loci controlling fetal haemoglobin production on chromosomes 11p and 6q by the regressive approach.

21 January 2018

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Haplotype mapping of a major quantitative-trait locus for fetal hemoglobin production, on chromosome 6q23.

21 January 2018

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Evidence of genetic interaction between the beta-globin complex and chromosome 8q in the expression of fetal hemoglobin

21 January 2018

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Quantitative trait locus on chromosome 8q influences the switch from fetal to adult hemoglobin.

21 January 2018

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Human γ-globin genes silenced independently of other genes in the β-globin locus

21 January 2018

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10.1111/J.1600-0609.2007.00970.X

21 January 2018

Identifiers

DOI

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26 December 2017

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26 December 2017