(Q46928382)

English

Regulation of protein kinase D activity in adult myocardium: novel counter-regulatory roles for protein kinase Cepsilon and protein kinase A.

scientific article published on 4 October 2007

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9 January 2020

Regulation of protein kinase D activity in adult myocardium: novel counter-regulatory roles for protein kinase Cepsilon and protein kinase A (English)

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9 January 2020

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9 January 2020

author name string

Robert S Haworth

1

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9 January 2020

Neil A Roberts

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9 January 2020

Friederike Cuello

3

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4 October 2007

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9 January 2020

Journal of Molecular and Cellular Cardiology

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9 January 2020

686-695

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9 January 2020

Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain

1 reference

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7 January 2021

Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase.

1 reference

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Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway.

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PKD in intestinal epithelial cells: rapid activation by phorbol esters, LPA, and angiotensin through PKC.

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Protein kinase D is a downstream target of protein kinase Ctheta

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Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D

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Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi network

1 reference

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Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane

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Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network

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7 January 2021

Protein kinase C mu selectively activates the mitogen-activated protein kinase (MAPK) p42 pathway

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Protein kinase C (PKC)eta-mediated PKC mu activation modulates ERK and JNK signal pathways

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Protein kinase D complexes with C-Jun N-terminal kinase via activation loop phosphorylation and phosphorylates the C-Jun N-terminus

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7 January 2021

Protein kinase D is sufficient to suppress EGF-induced c-Jun Ser 63 phosphorylation

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7 January 2021

Uncoupling of protein kinase D from suppression of EGF-dependent c-Jun phosphorylation in cancer cells

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Protein kinase C(mu) regulation of the JNK pathway is triggered via phosphoinositide-dependent kinase 1 and protein kinase C(epsilon)

1 reference

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Protein kinase C mu (PKC mu) associates with the B cell antigen receptor complex and regulates lymphocyte signaling

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7 January 2021

Co-transfection with protein kinase D confers phorbol-ester-mediated inhibition on glucagon-stimulated cAMP accumulation in COS cells transfected to overexpress glucagon receptors

1 reference

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7 January 2021

Expression and activity of protein kinase D/protein kinase C mu in myocardium: evidence for alpha1-adrenergic receptor- and protein kinase C-mediated regulation.

1 reference

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7 January 2021

Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5

1 reference

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7 January 2021

Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function

1 reference

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7 January 2021

Protein kinase D selectively targets cardiac troponin I and regulates myofilament Ca2+ sensitivity in ventricular myocytes.

1 reference

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7 January 2021

Regulation of the extracellular signal-regulated kinase pathway in adult myocardium: differential roles of G(q/11), Gi and G(12/13) proteins in signalling by alpha1-adrenergic, endothelin-1 and thrombin-sensitive protease-activated receptors.

1 reference

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7 January 2021

Effects of bisindolylmaleimide PKC inhibitors on p90RSK activity in vitro and in adult ventricular myocytes.

1 reference

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7 January 2021

Activation loop Ser744 and Ser748 in protein kinase D are transphosphorylated in vivo.

1 reference

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7 January 2021

Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu

1 reference

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7 January 2021

Dynamic re-distribution of protein kinase D (PKD) as revealed by a GFP-PKD fusion protein: dissociation from PKD activation

1 reference

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7 January 2021

Spatial and temporal regulation of protein kinase D (PKD)

1 reference

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7 January 2021

Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

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7 January 2021

AKAP-Lbc nucleates a protein kinase D activation scaffold

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7 January 2021

G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D: dependence on plasma membrane translocation and protein kinase Cepsilon

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7 January 2021

Regulation of protein kinase D by multisite phosphorylation. Identification of phosphorylation sites by mass spectrometry and characterization by site-directed mutagenesis

1 reference

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7 January 2021

PKCepsilon-PKD1 signaling complex at Z-discs plays a pivotal role in the cardiac hypertrophy induced by G-protein coupling receptor agonists

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7 January 2021

Protein kinase D inhibits plasma membrane Na(+)/H(+) exchanger activity

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Thrombin rapidly induces protein kinase D phosphorylation, and protein kinase C delta mediates the activation.

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Bombesin, vasopressin, endothelin, bradykinin, and platelet-derived growth factor rapidly activate protein kinase D through a protein kinase C-dependent signal transduction pathway.

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PKC-interacting proteins: from function to pharmacology

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Targeting protein kinase C activity reporter to discrete intracellular regions reveals spatiotemporal differences in agonist-dependent signaling

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Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain.

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Lipid raft disruption triggers protein kinase C and Src-dependent protein kinase D activation and Kidins220 phosphorylation in neuronal cells

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The pleckstrin homology domain of protein kinase D interacts preferentially with the eta isoform of protein kinase C

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Angiotensin II-induced protein kinase D activation is regulated by protein kinase Cdelta and mediated via the angiotensin II type 1 receptor in vascular smooth muscle cells.

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Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling

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Regulation by cAMP-dependent protein kinease of a G-protein-mediated phospholipase C.

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Role of phospholipase Cbeta3 phosphorylation in the desensitization of cellular responses to platelet-activating factor

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Identifiers

10.1016/J.YJMCC.2007.09.013

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17964599%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17964599%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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