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English
Pim2 complements Flt3 wild-type receptor in hematopoietic progenitor cell transformation.
scientific article published on 18 October 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
title
Pim2 complements Flt3 wild-type receptor in hematopoietic progenitor cell transformation
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
author
Hubert Serve
series ordinal
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Pavankumar N.G. Reddy
series ordinal
4
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stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
author name string
Agrawal S
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1
1 reference
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Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Koschmieder S
series ordinal
2
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stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Bäumer N
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Berdel WE
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Müller-Tidow C
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
publication date
18 October 2007
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
published in
Leukemia
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
volume
22
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
page(s)
78-86
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/sj.leu.2404988
0 references
cites work
The role of FLT3 in haematopoietic malignancies
1 reference
stated in
Crossref
reference URL
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Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines
1 reference
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Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations
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Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc
1 reference
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7 January 2021
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Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
1 reference
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7 January 2021
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AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.
1 reference
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7 January 2021
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FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model
1 reference
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7 January 2021
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Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
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7 January 2021
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Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis.
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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The pims and outs of survival signaling: role for the Pim-2 protein kinase in the suppression of apoptosis by cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
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7 January 2021
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The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
retrieved
7 January 2021
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inferred from DOI database lookup
The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
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7 January 2021
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Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.
1 reference
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7 January 2021
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inferred from DOI database lookup
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
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7 January 2021
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inferred from DOI database lookup
Targeting PIM kinases impairs survival of hematopoietic cells transformed by kinase inhibitor-sensitive and kinase inhibitor-resistant forms of Fms-like tyrosine kinase 3 and BCR/ABL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
retrieved
7 January 2021
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inferred from DOI database lookup
Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
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7 January 2021
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inferred from DOI database lookup
STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
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7 January 2021
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inferred from DOI database lookup
Complementary functions of the antiapoptotic protein A1 and serine/threonine kinase pim-1 in the BCR/ABL-mediated leukemogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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The oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
retrieved
7 January 2021
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inferred from DOI database lookup
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
retrieved
7 January 2021
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inferred from DOI database lookup
Pim-1 associates with protein complexes necessary for mitosis
1 reference
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Crossref
reference URL
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7 January 2021
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Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.
1 reference
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Crossref
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7 January 2021
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Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
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7 January 2021
based on heuristic
inferred from DOI database lookup
Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pim-1 kinase inhibits STAT5-dependent transcription via its interactions with SOCS1 and SOCS3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pim serine/threonine kinases regulate the stability of Socs-1 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404988
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.LEU.2404988
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
PubMed publication ID
17943165
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17943165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17943165%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
ResearchGate publication ID
5902781
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