(Q46954877)

26 December 2017

title

Nutritional upregulation of p85alpha expression is an early molecular manifestation of insulin resistance (English)

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26 December 2017

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M-A Cornier

1

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26 December 2017

D H Bessesen

2

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26 December 2017

I Gurevich

3

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26 December 2017

J W Leitner

4

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26 December 2017

B Draznin

5

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26 December 2017

publication date

21 February 2006

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26 December 2017

published in

Diabetologia

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26 December 2017

volume

49

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26 December 2017

issue

4

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26 December 2017

page(s)

748-754

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26 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-006-0148-0

exact match

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cites work

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-006-0148-0

The target of rapamycin (TOR) proteins

21 January 2018

1 reference

12 December 2020

Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase

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12 December 2020

Insulin resistance and cardiovascular disease

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12 December 2020

Cellular mechanisms of insulin resistance in humans

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12 December 2020

Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

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12 December 2020

Heated hand vein blood is satisfactory for measurements during free fatty acid kinetic studies

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12 December 2020

Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- mice

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12 December 2020

Amino acids and leucine allow insulin activation of the PKB/mTOR pathway in normal adipocytes treated with wortmannin and in adipocytes from db/db mice

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12 December 2020

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

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12 December 2020

Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

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12 December 2020

Identification of enhanced serine kinase activity in insulin resistance

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12 December 2020

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

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12 December 2020

Positive and Negative Roles of p85α and p85β Regulatory Subunits of Phosphoinositide 3-Kinase in Insulin Signaling

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12 December 2020

Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.

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12 December 2020

Turning down insulin signaling.

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12 December 2020

Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit

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12 December 2020

Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability.

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12 December 2020

Reversal of insulin resistance postpartum is linked to enhanced skeletal muscle insulin signaling

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12 December 2020

Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.

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12 December 2020

The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex

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12 December 2020

Insulin signaling in health and disease

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12 December 2020

Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle

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12 December 2020

Nutrient sensor links obesity with diabetes risk

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12 December 2020

A new method for the continuous monitoring of blood glucose by measurement of dissolved oxygen

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12 December 2020

Regulation of eIF-4E BP1 phosphorylation by mTOR.

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12 December 2020

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

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12 December 2020

Human placental growth hormone increases expression of the p85 regulatory unit of phosphatidylinositol 3-kinase and triggers severe insulin resistance in skeletal muscle

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12 December 2020

Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

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12 December 2020

Banting lecture 1988. Role of insulin resistance in human disease

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12 December 2020

Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes

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12 December 2020

Specific increase in p85alpha expression in response to dexamethasone is associated with inhibition of insulin-like growth factor-I stimulated phosphatidylinositol 3-kinase activity in cultured muscle cells

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12 December 2020

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

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12 December 2020

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

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12 December 2020

The TOR kinases link nutrient sensing to cell growth

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12 December 2020

10.1007/S00125-006-0148-0

Identifiers

DOI

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26 December 2017

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26 December 2017