(Q46968746)

English

Serotonin transporter phosphorylation by cGMP-dependent protein kinase is altered by a mutation associated with obsessive compulsive disorder

scientific article published in October 2007

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scholarly article

1 reference

Europe PubMed Central

27 December 2017

http://europepmc.org/abstract/MED/17913921

Serotonin transporter phosphorylation by cGMP-dependent protein kinase is altered by a mutation associated with obsessive compulsive disorder (English)

1 reference

Europe PubMed Central

27 December 2017

http://europepmc.org/abstract/MED/17913921

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phosphorylation

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based on heuristic

inferred from title

obsessive-compulsive disorder

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author name string

Yuan-Wei Zhang

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672823&resulttype=core&format=json

16 May 2020

Joan Gesmonde

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672823&resulttype=core&format=json

16 May 2020

Sammanda Ramamoorthy

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672823&resulttype=core&format=json

16 May 2020

Gary Rudnick

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672823&resulttype=core&format=json

16 May 2020

language of work or name

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publication date

1 October 2007

1 reference

Europe PubMed Central

27 December 2017

http://europepmc.org/abstract/MED/17913921

Journal of Neuroscience

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672823&resulttype=core&format=json

16 May 2020

27

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Europe PubMed Central

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16 May 2020

40

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672823&resulttype=core&format=json

16 May 2020

10878-10886

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672823&resulttype=core&format=json

16 May 2020

Mechanism of action of serotonin selective reuptake inhibitors. Serotonin receptors and pathways mediate therapeutic effects and side effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

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Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

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Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

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Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A.

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https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

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The medical benefit of 5-HT research

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https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

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Accessibility and conformational coupling in serotonin transporter predicted internal domains.

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https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

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A human serotonin transporter mutation causes constitutive activation of transport activity

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https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

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Analysis of the functional role of cGMP-dependent protein kinase in intact human platelets using a specific activator 8-para-chlorophenylthio-cGMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin transporter: gene, genetic disorders, and pharmacogenetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

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Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

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Stimulation of serotonin transport by the cyclic GMP phosphodiesterase-5 inhibitor sildenafil

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

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A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: evidence for distinct cellular mechanisms involved in transporter surface expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine-scanning mutagenesis of serotonin transporter intracellular loop 2 suggests an alpha-helical conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Support for the association between the rare functional variant I425V of the serotonin transporter gene and susceptibility to obsessive compulsive disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin transporter mutations associated with obsessive-compulsive disorder and phosphorylation alter binding affinity for inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytoplasmic substrate permeation pathway of serotonin transporter.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ibogaine, a noncompetitive inhibitor of serotonin transport, acts by stabilizing the cytoplasm-facing state of the transporter.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vaccinia-T7 RNA polymerase expression system: evaluation for the expression cloning of plasma membrane transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stoichiometric and reversible phosphorylation of a 46-kDa protein in human platelets in response to cGMP- and cAMP-elevating vasodilators

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine A3 receptors regulate serotonin transport via nitric oxide and cGMP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calmodulin-dependent regulation of the catalytic function of the human serotonin transporter in placental choriocarcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the human serotonin transporter. Cholera toxin-induced stimulation of serotonin uptake in human placental choriocarcinoma cells is accompanied by increased serotonin transporter mRNA levels and serotonin transporter-specific ligand bin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of external loop topology in the serotonin transporter by site-directed chemical labeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis and regulation of vasodilator-stimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain serotonin neurotransmission: an overview and update with an emphasis on serotonin subsystem heterogeneity, multiple receptors, interactions with other neurotransmitter systems, and consequent implications for understanding the actions of serot

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0034-07.2007

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672823&resulttype=core&format=json

16 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672823&resulttype=core&format=json

16 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672823&resulttype=core&format=json

16 May 2020

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