(Q46970598)

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Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients.

scientific article published on 4 June 2013

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2 March 2020

Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients (English)

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2 March 2020

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Franz-Josef Müller

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O Robicsek

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R Karry

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I Petit

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N Salman-Kesner

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E Klein

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D Ben-Shachar

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4 June 2013

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10

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Molecular Psychiatry

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2 March 2020

1067-1076

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10

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2 March 2020

https://scigraph.springernature.com/pub.10.1038/mp.2013.67

0 references

The environment and susceptibility to schizophrenia

1 reference

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Neurodevelopmental model of schizophrenia: update 2012

1 reference

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Synaptic changes in the brain of subjects with schizophrenia.

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Is dopamine neurotransmission altered in prodromal schizophrenia? A review of the evidence

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Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis.

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Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

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The dopamine hypothesis of schizophrenia: version III--the final common pathway

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Mesoprefrontal dopamine neurons and schizophrenia: role of developmental abnormalities

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Glutamate, dopamine, and schizophrenia: from pathophysiology to treatment

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The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

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Mitochondrial mutations and polymorphisms in psychiatric disorders

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Perturbation in mitochondrial network dynamics and in complex I dependent cellular respiration in schizophrenia

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Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

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Increased mitochondrial respiration maintains the mitochondrial membrane potential and promotes survival of cerebellar neurons in an endogenous model of glutamate receptor activation.

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The interplay between mitochondrial complex I, dopamine and Sp1 in schizophrenia

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Mitochondrial complex I as a novel target for intraneuronal DA: modulation of respiration in intact cells

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Dopamine toxicity involves mitochondrial complex I inhibition: implications to dopamine-related neuropsychiatric disorders

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Mitochondrial dysfunction in schizophrenia: a possible linkage to dopamine

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Modelling schizophrenia using human induced pluripotent stem cells

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Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia

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Disease-specific, neurosphere-derived cells as models for brain disorders

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Development of patient-specific neurons in schizophrenia using induced pluripotent stem cells.

1 reference

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Modeling psychiatric disorders at the cellular and network levels

1 reference

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Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient.

1 reference

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Pluripotent stem cells as a model to study oxygen metabolism in neurogenesis and neurodevelopmental disorders

1 reference

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Induced pluripotent stem cells from hair follicles as a cellular model for neurodevelopmental disorders.

1 reference

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21 January 2018

Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette.

1 reference

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21 January 2018

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

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A bioinformatic assay for pluripotency in human cells

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A guide to stem cell identification: progress and challenges in system-wide predictive testing with complex biomarkers.

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Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells

1 reference

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

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Dexamethasone enhances the norepinephrine-induced ERK/MAPK intracellular pathway possibly via dysregulation of the alpha2-adrenergic receptor: implications for antidepressant drug mechanism of action

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State-of-the-art of high-performance liquid chromatographic analysis of amino acids in physiological samples

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Dopamine modulates mitochondrial function in viable SH-SY5Y cells possibly via its interaction with complex I: relevance to dopamine pathology in schizophrenia.

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Neuronal differentiation of stem cells isolated from adult muscle.

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Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives.

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Pluripotent stem cell model reveals essential roles for miR-450b-5p and miR-184 in embryonic corneal lineage specification

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Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains

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Non-dopaminergic neurons partly expressing dopaminergic phenotype: distribution in the brain, development and functional significance.

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Dopamine neuron systems in the brain: an update

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Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient

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Schizophrenia as a disorder of disconnectivity

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Relative roles of the different Pax6 domains for pancreatic alpha cell development

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O-GlcNAc glycosylation: a signal for the nuclear transport of cytosolic proteins?

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Direct non-cell autonomous Pax6 activity regulates eye development in the zebrafish

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Nestin expression in human tumors and tumor cell lines.

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Differentiation of CD133+ stem cells from amyotrophic lateral sclerosis patients into preneuron cells

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Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients

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Death receptors and mitochondria: two prime triggers of neural apoptosis and differentiation

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Neuroanatomical pattern of mitochondrial complex I pathology varies between schizophrenia, bipolar disorder and major depression

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Derivation of midbrain dopamine neurons from human embryonic stem cells

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Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors

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Glutamate enhances survival and proliferation of neural progenitors derived from the subventricular zone.

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7 January 2021

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Mitochondrial Dysfunction and Dendritic Beading during Neuronal Toxicity

1 reference

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7 January 2021

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Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure

1 reference

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7 January 2021

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Symptom rating scales and outcome in schizophrenia.

1 reference

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7 January 2021

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Transporters buffer synaptically released glutamate on a submillisecond time scale.

1 reference

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7 January 2021

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Identifiers

10.1038/MP.2013.67

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732879%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

Europe PubMed Central

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2 March 2020

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