(Q46972864)

27 December 2017

editorial

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title

The road to LOAD: late-onset Alzheimer's disease and a possible way to block it. (English)

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27 December 2017

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James F Whitfield

1

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27 December 2017

language of work or name

English

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publication date

1 October 2007

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27 December 2017

Expert Opinion on Therapeutic Targets

published in

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27 December 2017

volume

11

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27 December 2017

issue

10

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27 December 2017

page(s)

1257-1260

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27 December 2017

Protein synthesis at synaptic sites on dendrites

cites work

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https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

Role of the Blood-Brain Barrier in the Pathogenesis of Alzheimers Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

IFN-gamma-induced BACE1 expression is mediated by activation of JAK2 and ERK1/2 signaling pathways and direct binding of STAT1 to BACE1 promoter in astrocytes

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

Interferon gamma stimulates beta-secretase expression and sAPPbeta production in astrocytes

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

Can statins put the brakes on Alzheimer's disease?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

Cholesterol level, statin use and Alzheimer's disease in adults with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

Down syndrome and beta-amyloid deposition

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

Glia-induced neuronal differentiation by transcriptional regulation

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

CNS synaptogenesis promoted by glia-derived cholesterol

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

Neurovascular mechanisms of Alzheimer's neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.11.10.1257

RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease

21 January 2018

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10.1517/14728222.11.10.1257

21 January 2018

Identifiers

DOI

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27 December 2017

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27 December 2017