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English
Nonadherent cells switch to a Rac-mediated, SHIP regulated, Akt activation mode for survival.
scientific article published in October 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
title
Nonadherent cells switch to a Rac-mediated, SHIP regulated, Akt activation mode for survival
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
author
Elisabeth Génot
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
author name string
B Chaigne-Delalande
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
G Anies
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
I Kramer
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
language of work or name
English
0 references
publication date
1 October 2007
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
volume
27
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
issue
13
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
page(s)
1876-1885
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
cites work
PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac1 protects epithelial cells against anoikis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI 3-kinase, Akt and cell survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrins and anoikis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
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7 January 2021
based on heuristic
inferred from DOI database lookup
The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential expression of integrin subunits on adherent and nonadherent mast cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipid phosphatases in the immune system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
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7 January 2021
based on heuristic
inferred from DOI database lookup
Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
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7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
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7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta1-integrin and PTEN control the phosphorylation of protein kinase C.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for Rac in Ras transformation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
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7 January 2021
based on heuristic
inferred from DOI database lookup
Anchorage dependence, integrins, and apoptosis
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pleckstrin homology domain of phospholipase C-beta2 as an effector site for Rac.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho family GTPases regulate VEGF-stimulated endothelial cell motility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The costimulation-regulated duration of PKB activation controls T cell longevity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substitution of an aspartic acid results in constitutive activation of c-kit receptor tyrosine kinase in a rat tumor mast cell line RBL-2H3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI 3-kinase: a pivotal pathway in T-cell activation?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of D-3 phosphoinositides during T cell activation via the T cell antigen receptor/CD3 complex and CD2 antigens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B and rac are activated in parallel within a phosphatidylinositide 3OH-kinase-controlled signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210830
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1210830
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
PubMed publication ID
17906692
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17906692
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17906692%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
ResearchGate publication ID
5937647
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