(Q46986653)

27 December 2017

title

Nonclinical toxicology assessments support the chronic safety of dapagliflozin, a first-in-class sodium-glucose cotransporter 2 inhibitor (English)

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27 December 2017

author name string

Mark Tirmenstein

1

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27 December 2017

Thomas E Dorr

2

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27 December 2017

Evan B Janovitz

3

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27 December 2017

Deborah Hagan

4

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27 December 2017

Lynn M Abell

5

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27 December 2017

Joelle M Onorato

6

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27 December 2017

Jean M Whaley

7

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27 December 2017

Michael J Graziano

8

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27 December 2017

Timothy P Reilly

9

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27 December 2017

publication date

1 September 2013

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27 December 2017

International Journal of Toxicology

published in

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27 December 2017

volume

32

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27 December 2017

issue

5

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27 December 2017

page(s)

336-350

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27 December 2017

Diabetes prevalence and therapeutic target achievement in the United States, 1999 to 2006.

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

Treatment approach and HbA1c control among US adults with type 2 diabetes: NHANES 1999-2004.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1091581813505331

SGLT2 inhibition--a novel strategy for diabetes treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

Targeting the kidney and glucose excretion with dapagliflozin: preclinical and clinical evidence for SGLT2 inhibition as a new option for treatment of type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

Differentiating sodium-glucose co-transporter-2 inhibitors in development for the treatment of type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

Molecular characteristics of Na(+)-coupled glucose transporters in adult and embryonic rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

Active sugar transport in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

Risk factors for renal dysfunction in type 2 diabetes: U.K. Prospective Diabetes Study 74.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

A novel method for the determination of 1,5-anhydroglucitol, a glycemic marker, in human urine utilizing hydrophilic interaction liquid chromatography/MS(3).

21 January 2018

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https://api.crossref.org/works/10.1177%2F1091581813505331

SGLT2 mediates glucose reabsorption in the early proximal tubule.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1091581813505331

SGLT2 deletion improves glucose homeostasis and preserves pancreatic beta-cell function

21 January 2018

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Effects of furosemide and the combination of furosemide and the labeled dosage of pimobendan on the circulating renin-angiotensin-aldosterone system in clinically normal dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

Rat cytosolic aspartate aminotransferase: regulation of its mRNA and contribution to gluconeogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

A missense mutation in the Na(+)/glucose cotransporter gene SGLT1 in a patient with congenital glucose-galactose malabsorption: normal trafficking but inactivation of the mutant protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

A contemporary overview of chronic progressive nephropathy in the laboratory rat, and its significance for human risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

Species comparison of postnatal bone growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

From victim to ally: the kidney as an emerging target for the treatment of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581813505331

21 January 2018

Identifiers

DOI

10.1177/1091581813505331

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27 December 2017

PubMed ID

24097127

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27 December 2017