(Q47070663)

5 January 2018

title

Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus. (English)

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5 January 2018

positive regulation of hh target transcription factor activity

main subject

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Gene Ontology release 2020-05-02

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Costa Dmel_CG1708

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Protein kinase, cAMP-dependent, catalytic subunit 1 Dmel_CG4379

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Suppressor of fused Dmel_CG6054

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author name string

Jianhang Jia

1

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5 January 2018

Kazuhito Amanai

2

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5 January 2018

Gelin Wang

3

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5 January 2018

Jiong Tang

4

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5 January 2018

Bing Wang

5

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5 January 2018

Jin Jiang

6

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5 January 2018

language of work or name

English

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publication date

24 March 2002

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5 January 2018

published in

Nature

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5 January 2018

volume

416

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5 January 2018

page(s)

548-552

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5 January 2018

issue

6880

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5 January 2018

https://scigraph.springernature.com/pub.10.1038/nature733

exact match

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cites work

Wnt signaling: a common theme in animal development

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Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor

21 January 2018

1 reference

Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator.

21 January 2018

1 reference

Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus.

21 January 2018

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Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

21 January 2018

1 reference

Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus

21 January 2018

1 reference

Signalling by hedgehog family proteins in Drosophila and vertebrate development

21 January 2018

1 reference

The sonic hedgehog-patched-gli pathway in human development and disease

21 January 2018

1 reference

Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein

21 January 2018

1 reference

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

21 January 2018

1 reference

GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis

21 January 2018

1 reference

Complementary and mutually exclusive activities of decapentaplegic and wingless organize axial patterning during Drosophila leg development.

21 January 2018

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Direct and long-range action of a wingless morphogen gradient.

21 January 2018

1 reference

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

21 January 2018

1 reference

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb.

21 January 2018

1 reference

Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway.

21 January 2018

1 reference

Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus

21 January 2018

1 reference

A molecular mechanism for the effect of lithium on development

21 January 2018

1 reference

GSK3, a master switch regulating cell-fate specification and tumorigenesis

21 January 2018

1 reference

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

21 January 2018

1 reference

Gli proteins and Hedgehog signaling: development and cancer

21 January 2018

1 reference

Tripartite signaling of pattern: interactions between Hedgehogs, BMPs and Wnts in the control of vertebrate development

21 January 2018

1 reference

Dual roles for patched in sequestering and transducing Hedgehog

21 January 2018

1 reference

Protein kinase A and hedgehog signaling in Drosophila limb development

21 January 2018

1 reference

Functional significance of a family of protein kinases encoded at the shaggy locus in Drosophila.

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE733

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5 January 2018

Dimensions Publication ID

0 references

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5 January 2018