(Q47071565)

5 January 2018

title

The spinal muscular atrophy protein SMN affects Drosophila germline nuclear organization through the U body-P body pathway (English)

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5 January 2018

cytoplasmic U snRNP body assembly

main subject

Drosophila

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spinal muscular atrophy

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based on heuristic

inferred from title

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1990194

Survival motor neuron Dmel_CG16725

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GOA release 2020-03-11

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Lin Lee

1

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5 January 2018

Siân E Davies

series ordinal

2

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5 January 2018

Ji-Long Liu

series ordinal

3

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5 January 2018

language of work or name

English

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publication date

21 May 2009

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5 January 2018

published in

Developmental Biology

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5 January 2018

volume

332

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5 January 2018

issue

1

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5 January 2018

page(s)

142-155

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5 January 2018

Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The SMN complex: an assembly machine for RNPs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The Gemin5 protein of the SMN complex identifies snRNAs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Genetic mapping of chronic childhood-onset spinal muscular atrophy to chromosome 5q11.2-13.3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Caenorhabditis elegans in the study of SMN-interacting proteins: a role for SMI-1, an orthologue of human Gemin2 and the identification of novel components of the SMN complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The carnegie protein trap library: a versatile tool for Drosophila developmental studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Neuromuscular defects in a Drosophila survival motor neuron gene mutant.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A role for Caenorhabditis elegans in understanding the function and interactions of human disease genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

P bodies: at the crossroads of post-transcriptional pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Cajal bodies: the first 100 years

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The centennial of the Cajal body.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Genetic homogeneity between acute and chronic forms of spinal muscular atrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Hrb27C, Sqd and Otu cooperatively regulate gurken RNA localization and mediate nurse cell chromosome dispersion in Drosophila oogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Establishment of four strains of cells from insect tissues grown in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The Schizosaccharomyces pombe protein Yab8p and a novel factor, Yip1p, share structural and functional similarity with the spinal muscular atrophy-associated proteins SMN and SIP1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A mouse model for spinal muscular atrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Survival motor neuron protein facilitates assembly of stress granules

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

U1 and U2 small nuclear RNAs are present in nuclear speckles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Disruption of GW bodies impairs mammalian RNA interference

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The role of GW/P-bodies in RNA processing and silencing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Translational regulation and RNA localization in Drosophila oocytes and embryos.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Giant polytene chromosomes from the ovaries of a Drosophila mutant.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Caenorhabditis elegans decapping proteins: localization and functional analysis of Dcp1, Dcp2, and DcpS during embryogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Genome-wide expression analysis of a spinal muscular atrophy model: towards discovery of new drug targets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Identification and characterization of a spinal muscular atrophy-determining gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Drosophila decapping protein 1, dDcp1, is a component of the oskar mRNP complex and directs its posterior localization in the oocyte.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Nuclear bodies in the Drosophila germinal vesicle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The Drosophila melanogaster Cajal body

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

U bodies are cytoplasmic structures that contain uridine-rich small nuclear ribonucleoproteins and associate with P bodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Coilin is essential for Cajal body organization in Drosophila melanogaster.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A novel nuclear structure containing the survival of motor neurons protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Essential role for a heterogeneous nuclear ribonucleoprotein (hnRNP) in oogenesis: hrp40 is absent from the germ line in the dorsoventral mutant squid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

SMN-mediated assembly of RNPs: a complex story

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The Caenorhabditis elegans orthologue of the human gene responsible for spinal muscular atrophy is a maternal product critical for germline maturation and embryonic viability.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Disruption of SMN function by ectopic expression of the human SMN gene in Drosophila.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

International SMA consortium meeting. (26-28 June 1992, Bonn, Germany)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Drosophila cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

P bodies and the control of mRNA translation and degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

The survival motor neuron protein of Schizosacharomyces pombe. Conservation of survival motor neuron interaction domains in divergent organisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Incidence, prevalence, and gene frequency studies of chronic childhood spinal muscular atrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Essential role for the SMN complex in the specificity of snRNP assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

In vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Monoclonal autoantibody from a (New Zealand black x New Zealand white)F1 mouse and some human scleroderma sera target an Mr 34,000 nucleolar protein of the U3 RNP particle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Missense mutation clustering in the survival motor neuron gene: a role for a conserved tyrosine and glycine rich region of the protein in RNA metabolism?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Half pint regulates alternative splice site selection in Drosophila.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Cup is an eIF4E binding protein required for both the translational repression of oskar and the recruitment of Barentsz

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

Efficient protein trafficking requires trailer hitch, a component of a ribonucleoprotein complex localized to the ER in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

A sponge-like structure involved in the association and transport of maternal products during Drosophila oogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.05.553

10.1016/J.YDBIO.2009.05.553

7 January 2021

Identifiers

DOI

1 reference

5 January 2018

1 reference

5 January 2018