(Q47098601)

8 January 2018

title

AMPK: a cellular energy sensor primarily regulated by AMP. (English)

1 reference

8 January 2018

author name string

Graeme J Gowans

series ordinal

1

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8 January 2018

D Grahame Hardie

series ordinal

2

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8 January 2018

publication date

1 February 2014

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8 January 2018

Biochemical Society Transactions

published in

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8 January 2018

volume

42

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8 January 2018

issue

1

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8 January 2018

page(s)

71-75

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8 January 2018

AMP is a true physiological regulator of AMP-activated protein kinase by both allosteric activation and enhancing net phosphorylation

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AMP-activated protein kinase: new regulation, new roles?

23 May 2018

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AMP-activated protein kinase undergoes nucleotide-dependent conformational changes

23 May 2018

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AMPK: a nutrient and energy sensor that maintains energy homeostasis

23 May 2018

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AMPK functions as an adenylate charge-regulated protein kinase.

23 May 2018

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Structure of mammalian AMPK and its regulation by ADP

23 May 2018

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β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)

23 May 2018

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Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation

23 May 2018

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Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.

23 May 2018

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Structural basis for AMP binding to mammalian AMP-activated protein kinase

23 May 2018

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Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

23 May 2018

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5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

23 May 2018

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Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

23 May 2018

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Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

23 May 2018

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The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

23 May 2018

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Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.

23 May 2018

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CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

23 May 2018

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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

Phosphotransfer networks and cellular energetics

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

AMPK beta subunit targets metabolic stress sensing to glycogen

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

AMP-activated protein kinase: the energy charge hypothesis revisited

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

The regulation of AMP-activated protein kinase by phosphorylation

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

The structure of a domain common to archaebacteria and the homocystinuria disease protein

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

Activation of rat liver cytosolic 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase by adenosine 5'-monophosphate.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

The low activity of acetyl-CoA carboxylase in basal and glucagon-stimulated hepatocytes is due to phosphorylation by the AMP-activated protein kinase and not cyclic AMP-dependent protein kinase.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

Reversible modulation of the activities of both liver microsomal hydroxymethylglutaryl coenzyme A reductase and its inactivating enzyme. Evidence for regulation by phosphorylation-dephosphorylation

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

AMPK is a direct adenylate charge-regulated protein kinase.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703408

The regulation of AMP-activated protein kinase by phosphorylation

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1042%2FBST20130244

Regulation of hepatic acetyl coenzyme A carboxylase by phosphorylation and dephosphorylation

21 January 2018

1 reference

12 December 2020

Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol

1 reference

12 December 2020

Role of the AMP-activated protein kinase in the cellular stress response

1 reference

12 December 2020

5'-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms

1 reference

12 December 2020

Regulation of rat liver acetyl-CoA carboxylase. Regulation of phosphorylation and inactivation of acetyl-CoA carboxylase by the adenylate energy charge

1 reference

12 December 2020

A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis

1 reference

12 December 2020

Identifiers

DOI

10.1042/BST20130244

1 reference

8 January 2018

PMC publication ID

5703408

1 reference

8 January 2018

PubMed publication ID

24450630

1 reference

8 January 2018