(Q47151363)

English

Longitudinal measures of cognition in the Ts65Dn mouse: Refining windows and defining modalities for therapeutic intervention in Down syndrome.

scientific article published on 5 February 2016

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scholarly article

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Europe PubMed Central

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7 March 2020

Longitudinal measures of cognition in the Ts65Dn mouse: Refining windows and defining modalities for therapeutic intervention in Down syndrome (English)

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7 March 2020

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7 March 2020

author name string

J Luis Olmos-Serrano

1

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7 March 2020

William A Tyler

2

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7 March 2020

Howard J Cabral

3

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7 March 2020

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24 February 2016

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7 March 2020

Experimental Neurology

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7 March 2020

279

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7 March 2020

40-56

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7 March 2020

An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice

1 reference

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23 May 2018

Executive functions among youth with Down Syndrome and co-existing neurobehavioural disorders.

1 reference

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23 May 2018

A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials

1 reference

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Pre-reproductive maternal enrichment influences rat maternal care and offspring developmental trajectories: behavioral performances and neuroplasticity correlates.

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Beneficial effects of the β-secretase inhibitor GRL-8234 in 5XFAD Alzheimer's transgenic mice lessen during disease progression

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23 May 2018

Down syndrome and Alzheimer's disease: Common pathways, common goals

1 reference

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23 May 2018

Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome

1 reference

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1 reference

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23 May 2018

Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome

1 reference

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23 May 2018

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

1 reference

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Linking the developmental and degenerative theories of schizophrenia: association between infant development and adult cognitive decline

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23 May 2018

Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficits

1 reference

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23 May 2018

Atypical aging in Down syndrome

1 reference

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23 May 2018

Aging and intellectual disability: insights from mouse models of Down syndrome

1 reference

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23 May 2018

Non-spatial pre-training in the water maze as a clinically relevant model for evaluating learning and memory in experimental TBI.

1 reference

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23 May 2018

Systematic review of cognitive development across childhood in Down syndrome: implications for treatment interventions

1 reference

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23 May 2018

Neurodevelopmental and psychiatric issues in Down's syndrome: assessment and intervention.

1 reference

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23 May 2018

Early interactions with mother and peers independently build adult social skills and shape BDNF and oxytocin receptor brain levels

1 reference

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23 May 2018

Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model.

1 reference

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23 May 2018

The in vivo Down syndrome genomic library in mouse

1 reference

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23 May 2018

Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: a putative model of gene × environment interaction

1 reference

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23 May 2018

Low sociability in BTBR T+tf/J mice is independent of partner strain

1 reference

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23 May 2018

Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

23 May 2018

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

23 May 2018

Hippocampal-dependent spatial memory in the water maze is preserved in an experimental model of temporal lobe epilepsy in rats

1 reference

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23 May 2018

The use of mouse models to understand and improve cognitive deficits in Down syndrome

1 reference

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23 May 2018

Animal models of prefrontal-executive function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

23 May 2018

α-Tocopherol suppresses lipid peroxidation and behavioral and cognitive impairments in the Ts65Dn mouse model of Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

23 May 2018

Updated national birth prevalence estimates for selected birth defects in the United States, 2004-2006

1 reference

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Developing language in a developing body: the relationship between motor development and language development.

1 reference

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23 May 2018

Does the learning deficit observed under an incremental repeated acquisition schedule of reinforcement in Ts65Dn mice, a model for Down syndrome, change as they age?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

23 May 2018

What is the Most Sensitive Measure of Water Maze Probe Test Performance?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

23 May 2018

Prevention of developmental delays in a Down syndrome mouse model

1 reference

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23 May 2018

The elusive nature of executive functions: a review of our current understanding

1 reference

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23 May 2018

Differential regulation of fronto-executive function by the monoamines and acetylcholine

1 reference

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23 May 2018

Infant developmental milestones and subsequent cognitive function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

23 May 2018

Morris water maze: procedures for assessing spatial and related forms of learning and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

23 May 2018

Executive function and the frontal lobes: a meta-analytic review

1 reference

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23 May 2018

Mouse models of cognitive disorders in trisomy 21: a review

1 reference

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23 May 2018

DEVELOPMENTAL COMPARISONS OF MENTALLY RETARDED AND NEUROTIC CHILDREN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

23 May 2018

Behavioral profiles of inbred strains on novel olfactory, spatial and emotional tests for reference memory in mice

1 reference

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23 May 2018

The neurobiological basis of spontaneous alternation

1 reference

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23 May 2018

Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome

1 reference

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23 May 2018

Cognitive and neurobiologic markers of early Alzheimer disease

1 reference

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23 May 2018

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

1 reference

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23 May 2018

Segmental trisomy as a mouse model for Down syndrome

1 reference

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23 May 2018

Psychomotor development in the first year and mental retardation--a prospective study.

1 reference

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23 May 2018

Neonatal frontal lesions in hamsters impair species-typical behaviors and reduce brain weight and neocortical thickness

1 reference

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23 May 2018

A summary of recent research into the development of children with Down's syndrome.

1 reference

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23 May 2018

Down syndrome children often have brain with maturation delay, retardation of growth, and cortical dysgenesis.

1 reference

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23 May 2018

Learning difficulties in infants with Downʼs syndrome

1 reference

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23 May 2018

Neuroanatomical correlates of sparing of function after neonatal medial prefrontal cortex lesions in rats.

1 reference

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23 May 2018

Relationship between motor skill competency and executive function in children with Down's syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Nest building is impaired in the Ts65Dn mouse model of Down syndrome and rescued by blocking 5HT2a receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Rule-based category learning in Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Obstructive sleep apnea syndrome and cognition in Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Water T-maze: a useful assay for determination of repetitive behaviors in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Cognitive flexibility among individuals with Down syndrome: assessing the influence of verbal and nonverbal abilities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Impairment of nesting behaviour in 3xTg-AD mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Learning to walk changes infants' social interactions.

1 reference

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15 August 2018

Age-related cognitive decline and nesting behavior in an APPswe/PS1 bigenic model of Alzheimer's disease.

1 reference

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15 August 2018

Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5716476

15 August 2018

Working memory, processing speed, and set-shifting in children with developmental coordination disorder and attention-deficit-hyperactivity disorder.

1 reference

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15 August 2018

[Neuropsychological impairment in the early Alzheimer's disease]

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15 August 2018

Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1.

1 reference

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15 August 2018

Assessing nest building in mice.

1 reference

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15 August 2018

Early discrimination reversal learning impairment and preserved spatial learning in a longitudinal study of Tg2576 APPsw mice.

1 reference

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15 August 2018

Infant motor development is associated with adult cognitive categorisation in a longitudinal birth cohort study.

1 reference

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15 August 2018

Infant developmental milestones: a 31-year follow-up

1 reference

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15 August 2018

Experimental parameters affecting the Morris water maze performance of a mouse model of Down syndrome.

1 reference

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15 August 2018

Motor dysfunction in a mouse model for Down syndrome.

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15 August 2018

International trends of Down syndrome 1993-2004: Births in relation to maternal age and terminations of pregnancies

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3 November 2018

Reflex-ontogeny and behavioural development of the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/26854932

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor performance of children with Down syndrome and typical development at 2 to 4 and 26 months

1 reference

https://pubmed.ncbi.nlm.nih.gov/26854932

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EXPNEUROL.2016.02.005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26854932%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26854932%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26854932%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

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