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The TRPM2 ion channel is required for sensitivity to warmth.
scientific article published on 17 August 2016
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scholarly article
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Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
title
The TRPM2 ion channel is required for sensitivity to warmth
(English)
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
author
Peter A McNaughton
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
Chun-Hsiang Tan
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
author name string
Chun-Hsiang Tan
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
5720344
retrieved
10 January 2018
reference URL
http://europepmc.org/abstract/PMC/5720344
language of work or name
English
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publication date
17 August 2016
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
published in
Nature
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
volume
536
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
page(s)
460-463
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
issue
7617
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
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ImageJ
1 reference
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Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5720344/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
exact match
https://scigraph.springernature.com/pub.10.1038/nature19074
0 references
cites work
Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
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23 May 2018
Peripheral thermosensation in mammals
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons
1 reference
stated in
PubMed Central
reference URL
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retrieved
23 May 2018
TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin
1 reference
stated in
PubMed Central
reference URL
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retrieved
23 May 2018
TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
TRPM3 is a nociceptor channel involved in the detection of noxious heat
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
Lack of TRPM2 impaired insulin secretion and glucose metabolisms in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
Cellular and Molecular Mechanisms of Pain
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
1 reference
stated in
PubMed Central
reference URL
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retrieved
23 May 2018
TRPV1 unlike TRPV2 is restricted to a subset of mechanically insensitive cutaneous nociceptors responding to heat
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
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23 May 2018
Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
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23 May 2018
The menthol receptor TRPM8 is the principal detector of environmental cold
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
Insights into TRPM4 function, regulation and physiological role.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
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23 May 2018
Lessons from peppers and peppermint: the molecular logic of thermosensation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
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23 May 2018
Non-radioactive in situ hybridization: simplified procedures for use in whole-mounts of mouse and chick embryos
1 reference
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PubMed Central
reference URL
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23 May 2018
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
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23 May 2018
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
1 reference
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23 May 2018
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
1 reference
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PubMed Central
reference URL
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23 May 2018
A capsaicin-receptor homologue with a high threshold for noxious heat
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
23 May 2018
A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
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23 May 2018
A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF.
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retrieved
23 May 2018
TRPM2 mediates the lysophosphatidic acid-induced neurite retraction in the developing brain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
15 August 2018
Aminoethoxydiphenyl borate and flufenamic acid inhibit Ca2+ influx through TRPM2 channels in rat dorsal root ganglion neurons activated by ADP-ribose and rotenone.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
15 August 2018
Altered thermal sensitivity in neurons injured by infraorbital nerve lesion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
15 August 2018
Noxious heat activates all capsaicin-sensitive and also a sub-population of capsaicin-insensitive dorsal root ganglion neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720344
retrieved
15 August 2018
Nociceptors Lacking TRPV1 and TRPV2 Have Normal Heat Responses
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27533035
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/NATURE19074
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
Dimensions Publication ID
1040626845
0 references
PMCID
5720344
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
PubMed ID
27533035
1 reference
stated in
Europe PubMed Central
PMCID
5720344
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27533035%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
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