(Q47236966)

English

Connexin 43 gap junctions contribute to brain endothelial barrier hyperpermeability in familial cerebral cavernous malformations type III by modulating tight junction structure

scientific article published on 2 January 2018

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scholarly article

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

Connexin 43 gap junctions contribute to brain endothelial barrier hyperpermeability in familial cerebral cavernous malformations type III by modulating tight junction structure (English)

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

author name string

Allison M Johnson

1

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

James P Roach

2

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

Anna Hu

3

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

Svetlana M Stamatovic

4

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

Michal R Zochowski

5

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

Richard F Keep

6

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

Anuska V Andjelkovic

7

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

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publication date

2 January 2018

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5901390/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The connexin 43 C-terminus: A tail of many tales.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Mitogen-activated Protein Kinase (MAPK) Activated by Prostaglandin E2 Phosphorylates Connexin 43 and Closes Osteocytic Hemichannels in Response to Continuous Flow Shear Stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Role of connexin 43 in vascular hyperpermeability and relationship to Rock1-MLC20 pathway in septic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Changes in endothelial connexin 43 expression inversely correlate with microvessel permeability and VE-cadherin expression in endotoxin-challenged lungs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Vascular permeability in cerebral cavernous malformations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Connexins: junctional and non-junctional modulators of proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Gap junction protein connexin43 exacerbates lung vascular permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Gap junction regulation by calmodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

STRIPAK complexes: structure, biological function, and involvement in human diseases

1 reference

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2 November 2018

Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Retinoic acid regulates gap junction intercellular communication in human endometrial stromal cells through modulation of the phosphorylation status of connexin 43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Ultrastructural analysis of vascular features in cerebral cavernous malformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Loss of cerebral cavernous malformation 3 (Ccm3) in neuroglia leads to CCM and vascular pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Cortactin/tyrosine-phosphorylated cortactin interaction with connexin 43 in mouse seminiferous tubules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Connexins, cell motility, and the cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Zonula occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Connexin43 phosphorylation: structural changes and biological effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Structure and function of claudins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Proteomic identification of the cerebral cavernous malformation signaling complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Ultrastructural characteristics of hemorrhagic, nonhemorrhagic, and recurrent cavernous malformations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Connexin43 PDZ2 binding domain mutants create functional gap junctions and exhibit altered phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Effects of the chemokine CCL2 on blood-brain barrier permeability during ischemia-reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

A proposed role for ZO-1 in targeting connexin 43 gap junctions to the endocytic pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Connexin43 and connexin45 form heteromeric gap junction channels in which individual components determine permeability and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Inhibition of connexin43 gap junctional intercellular communication by TPA requires ERK activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Gap-junction-mediated propagation and amplification of cell injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

An in vitro model for endothelial permeability: assessment of monolayer integrity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901390

2 November 2018

Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/29295866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed

1 reference

https://pubmed.ncbi.nlm.nih.gov/29295866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the calmodulin binding domain of connexin 43

1 reference

https://pubmed.ncbi.nlm.nih.gov/29295866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1096/FJ.201700699R

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

0 references

1 reference

Europe PubMed Central

12 January 2018

http://europepmc.org/abstract/MED/29295866

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