(Q47273034)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

review article

1 reference

title

Estimation of blood-brain barrier crossing of drugs using molecular size and shape, and H-bonding descriptors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

author name string

van de Waterbeemd H

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Camenisch G

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Chretien JR

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Raevsky OA

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

publication date

1 January 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

Journal of Drug Targeting

8 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

page(s)

151-165

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9886238%20AND%20SRC:MED&resulttype=core&format=json

Role of hydrogen bonding in general anesthesia.

8 December 2019

cites work

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

On the partition of ampholytes: application to blood-brain distribution.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

The blood-brain barrier: principles for targeting peptides and drugs to the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Animal models for studying transport across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Review of theoretical passive drug absorption models: historical background, recent developments and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Hydrogen bonding potential as a determinant of the in vitro and in situ blood-brain barrier permeability of peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Physical parameters for brian uptake: optimizing log P, log D and pKa of T H A

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Hydrophobicity and central nervous system agents: on the principle of minimal hydrophobicity in drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

3'-(Arylmethyl)- and 3'-(aryloxy)-3-phenyl-4-hydroxyquinolin-2(1H)-ones: orally active antagonists of the glycine site on the NMDA receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Partition coefficients and their uses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Structural Requirements for Centrally Acting Drugs I

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Computation of brain-blood partitioning of organic solutes via free energy calculations.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

GABA-uptake inhibitors: construction of a general pharmacophore model and successful prediction of a new representative

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Polar molecular surface properties predict the intestinal absorption of drugs in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Effect of size and charge on the passive diffusion of peptides across Caco-2 cell monolayers via the paracellular pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Substance P and antagonists. Surface activity and molecular shapes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

A method to determine the ability of drugs to diffuse through the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Carrier-mediated intestinal transport of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

The relationship between permeant size and permeability in lipid bilayer membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889

Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10611869808997889