(Q47342620)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

0 references

5

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9 February 2020

Cécile Legallais

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Régis Baudoin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jean Matthieu Prot

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Grégory Nicolas

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jessy Brocheton

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Henri Benech

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Eric Leclerc

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

25 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

140-152

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver.

9 February 2020

cites work

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Transcellular transport of fluorescein in hepatocyte monolayers: evidence for functional polarity of cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Toxicity testing: creating a revolution based on new technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

The need for a new toxicity testing and risk analysis paradigm to implement REACH or any other large scale testing initiative

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Tissue engineering--current challenges and expanding opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Liver cell models in in vitro toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Use of hepatocyte cultures for the study of hepatotoxic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Chemical regulators have overreached

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Evaluation of fresh and cryopreserved hepatocytes as in vitro drug metabolism tools for the prediction of metabolic clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

A microfluidic hepatic coculture platform for cell-based drug metabolism studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Metabolomics-on-a-chip and metabolic flux analysis for label-free modeling of the internal metabolism of HepG2/C3A cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Prediction of the pharmacokinetics of atorvastatin, cerivastatin, and indomethacin using kinetic models applied to isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Microfabricated grooved substrates as platforms for bioartificial liver reactors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Inhibition and induction of human cytochrome P450 enzymes: current status

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Functional behavior of primary rat liver cells in a three-dimensional perfused microarray bioreactor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Improvement of HepG2/C3a cell functions in a microfluidic biochip

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Metabolomics-on-a-chip and predictive systems toxicology in microfluidic bioartificial organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Effects of oxygenation and flow on the viability and function of rat hepatocytes cocultured in a microchannel flat-plate bioreactor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Mechanisms of cytochrome P450 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

Prediction of hepatic metabolic clearance: comparison and assessment of prediction models

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.706725

10.3109/00498254.2012.706725

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22830982%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference