(Q47446156)

16 January 2018

title

Decreased blood-brain leptin transfer in an ovine model of obesity and weight loss: resolving the cause of leptin resistance (English)

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16 January 2018

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C L Adam

1

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16 January 2018

P A Findlay

series ordinal

2

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16 January 2018

language of work or name

English

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publication date

9 February 2010

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16 January 2018

International Journal of Obesity

published in

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16 January 2018

volume

34

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16 January 2018

issue

6

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16 January 2018

page(s)

980-988

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16 January 2018

Impaired transport of leptin across the blood-brain barrier in obesity is acquired and reversible

cites work

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https://api.crossref.org/works/10.1038%2FIJO.2010.28

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The blood-brain barrier as a cause of obesity

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Recent advances in understanding leptin signaling and leptin resistance

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Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

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Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans

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7 January 2021

Correlation between body weight (epididymal fat) and permeation rate of serum leptin through the blood-brain barrier (BBB) in male rats aged 8 months

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7 January 2021

Molecular mechanisms associated with leptin resistance: n-3 polyunsaturated fatty acids induce alterations in the tight junction of the brain

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7 January 2021

Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

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7 January 2021

Effect of weight loss on some serum cytokines in human obesity: increase in IL-10 after weight loss

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Nutritional influences on reproductive neuroendocrine output: insulin, leptin, and orexigenic neuropeptide signaling in the ovine hypothalamus.

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Seasonal and dose-dependent effects of intracerebroventricular leptin on lh secretion and appetite in sheep

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7 January 2021

Daily patterns of plasma leptin in sheep: effects of photoperiod and food intake

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7 January 2021

Blood-brain leptin transport and appetite and reproductive neuroendocrine responses to intracerebroventricular leptin injection in sheep: influence of photoperiod.

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Leptin enters the brain by a saturable system independent of insulin

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Hypothalamic gene expression in sheep for cocaine- and amphetamine-regulated transcript, pro-opiomelanocortin, neuropeptide Y, agouti-related peptide and leptin receptor and responses to negative energy balance

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Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial

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7 January 2021

Positron emission tomography shows that intrathecal leptin reaches the hypothalamus in baboons.

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7 January 2021

Tat-modified leptin is more accessible to hypothalamus through brain-blood barrier with a significant inhibition of body-weight gain in high-fat-diet fed mice

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7 January 2021

Triglycerides induce leptin resistance at the blood-brain barrier

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7 January 2021

Circulating leptin has saturable transport into intrathecal space in humans

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7 January 2021

Central leptin insufficiency syndrome: an interactive etiology for obesity, metabolic and neural diseases and for designing new therapeutic interventions

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7 January 2021

Identifiers

DOI

10.1038/IJO.2010.28

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16 January 2018

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16 January 2018