(Q47592080)

4 February 2018

title

The impact of the mTOR inhibitor sirolimus on the proliferation and function of pancreatic islets and ductal cells (English)

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4 February 2018

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C T Bussiere

1

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4 February 2018

J R T Lakey

series ordinal

2

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4 February 2018

A M J Shapiro

series ordinal

3

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4 February 2018

G S Korbutt

series ordinal

4

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4 February 2018

publication date

9 August 2006

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4 February 2018

published in

Diabetologia

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4 February 2018

volume

49

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4 February 2018

issue

10

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4 February 2018

page(s)

2341-2349

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4 February 2018

https://scigraph.springernature.com/pub.10.1007/s00125-006-0374-5

exact match

0 references

cites work

Endogenous Pancreatic Enzyme Activity Levels Show no Significant Effect on Human Islet Isolation Yield

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-006-0374-5

Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-006-0374-5

Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

21 January 2018

1 reference

12 December 2020

Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets

1 reference

12 December 2020

Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently

1 reference

12 December 2020

In vitro cultivation of human islets from expanded ductal tissue

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12 December 2020

Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways

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12 December 2020

Insulin release and suppression by tacrolimus, rapamycin and cyclosporin A are through regulation of the ATP-sensitive potassium channel

1 reference

12 December 2020

Rapamycin-induced endothelial cell death and tumor vessel thrombosis potentiate cytotoxic therapy against pancreatic cancer

1 reference

12 December 2020

Regulation of both glycogen synthase and PHAS-I by insulin in rat skeletal muscle involves mitogen-activated protein kinase-independent and rapamycin-sensitive pathways

1 reference

12 December 2020

Rapamycin effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties

1 reference

12 December 2020

Rapamycin inhibits human adipocyte differentiation in primary culture

1 reference

12 December 2020

Secretory defects induced by immunosuppressive agents on human pancreatic beta-cells

1 reference

12 December 2020

Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion.

1 reference

12 December 2020

Generation of islets of Langerhans from adult pancreatic stem cells

1 reference

12 December 2020

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

1 reference

12 December 2020

Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes.

1 reference

12 December 2020

Pancreatic stem cells

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12 December 2020

Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis

1 reference

12 December 2020

The beta cell transcription factors and development of the pancreas

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12 December 2020

Cold storage of rat pancreas before purification of islet beta-cells

1 reference

12 December 2020

Improvement in islet yield from a cold-preserved pancreas by pancreatic ductal collagenase distention at the time of harvesting

1 reference

12 December 2020

Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates

1 reference

12 December 2020

Insulin independence following isolated islet transplantation and single islet infusions

1 reference

12 December 2020

Attenuation of insulin-stimulated insulin receptor substrate-1 serine 307 phosphorylation in insulin resistance of type 2 diabetes.

1 reference

12 December 2020

Immunopharmacology of rapamycin

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12 December 2020

Inhibitory effects of immunosuppressive drugs on insulin secretion from HIT-T15 cells and Wistar rat islets

1 reference

12 December 2020

Endogenous pancreatic enzyme activity levels show no significant effect on human islet isolation yield

1 reference

12 December 2020

The portal immunosuppressive storm: relevance to islet transplantation?

1 reference

12 December 2020

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

1 reference

12 December 2020

Rapamycin inhibits constitutive p70s6k phosphorylation, cell proliferation, and colony formation in small cell lung cancer cells

1 reference

12 December 2020

Large scale isolation, growth, and function of porcine neonatal islet cells

1 reference

12 December 2020

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

1 reference

12 December 2020

Five-year follow-up after clinical islet transplantation

1 reference

12 December 2020

Role of endothelial cells in early pancreas and liver development

1 reference

12 December 2020

Islet Regeneration During the Reversal of Autoimmune Diabetes in NOD Mice

1 reference

12 December 2020

In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion

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12 December 2020

Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome

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12 December 2020

Sirolimus: its discovery, biological properties, and mechanism of action

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12 December 2020

Adenovirus-mediated XIAP gene transfer reverses the negative effects of immunosuppressive drugs on insulin secretion and cell viability of isolated human islets.

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12 December 2020

Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis

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12 December 2020

Rapamycin impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells

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12 December 2020

10.1007/S00125-006-0374-5

Identifiers

DOI

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4 February 2018

PubMed ID

16896936

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4 February 2018