(Q47647748)

4 February 2018

title

Chronic Administration of the N-Methyl-D-Aspartate Receptor Antagonist Ketamine Improves Rett Syndrome Phenotype (English)

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4 February 2018

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Annarita Patrizi

1

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4 February 2018

Nathalie Picard

2

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4 February 2018

Alex Joseph Simon

3

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4 February 2018

Georgia Gunner

4

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4 February 2018

Eleonora Centofante

5

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4 February 2018

Nick Arthur Andrews

6

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4 February 2018

Michela Fagiolini

7

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4 February 2018

language of work or name

English

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publication date

24 August 2015

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4 February 2018

published in

Biological Psychiatry

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4 February 2018

volume

79

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4 February 2018

issue

9

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4 February 2018

page(s)

755-764

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4 February 2018

Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model.

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Development of amino acid receptors in frontal cortex from girls with Rett syndrome

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Synaptic circuit abnormalities of motor-frontal layer 2/3 pyramidal neurons in a mutant mouse model of Rett syndrome

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Norketamine, the main metabolite of ketamine, is a non-competitive NMDA receptor antagonist in the rat cortex and spinal cord.

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12 December 2020

The MeCP2-null mouse hippocampus displays altered basal inhibitory rhythms and is prone to hyperexcitability.

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12 December 2020

Mechanisms underlying differential effectiveness of memantine and ketamine in rapid antidepressant responses

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12 December 2020

Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder

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12 December 2020

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

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12 December 2020

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12 December 2020

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12 December 2020

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Oral treatment with desipramine improves breathing and life span in Rett syndrome mouse model

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12 December 2020

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

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12 December 2020

Ketamine-induced hyperlocomotion associated with alteration of presynaptic components of dopamine neurons in the nucleus accumbens of mice

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12 December 2020

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12 December 2020

(+/-) Ketamine-induced prepulse inhibition deficits of an acoustic startle response in rats are not reversed by antipsychotics.

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12 December 2020

Sub-anesthetic concentrations of (R,S)-ketamine metabolites inhibit acetylcholine-evoked currents in α7 nicotinic acetylcholine receptors.

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12 December 2020

Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment

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12 December 2020

Enhancing ketamine translational pharmacology via receptor occupancy normalization

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12 December 2020

NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex

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12 December 2020

Altered development of glutamate and GABA receptors in the basal ganglia of girls with Rett syndrome

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12 December 2020

Network hyperexcitability in hippocampal slices from Mecp2 mutant mice revealed by voltage-sensitive dye imaging.

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12 December 2020

BDNF deregulation in Rett syndrome

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12 December 2020

10.1016/J.BIOPSYCH.2015.08.018

Identifiers

DOI

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4 February 2018

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4 February 2018