(Q47678853)

4 February 2018

title

Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells (English)

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4 February 2018

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V D Makhey

1

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4 February 2018

A Guo

2

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4 February 2018

D A Norris

3

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4 February 2018

P Hu

4

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4 February 2018

J Yan

5

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4 February 2018

P J Sinko

6

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4 February 2018

publication date

1 August 1998

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4 February 2018

published in

Pharmaceutical Research

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4 February 2018

volume

15

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4 February 2018

issue

8

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4 February 2018

page(s)

1160-1167

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4 February 2018

Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies.

cites work

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12 December 2020

Structure and function of P-glycoprotein in normal liver and small intestine

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12 December 2020

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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12 December 2020

Polarized transport of docetaxel and vinblastine mediated by P-glycoprotein in human intestinal epithelial cell monolayers

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12 December 2020

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

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12 December 2020

Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers

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12 December 2020

Evidence for a polarized efflux system in CACO-2 cells capable of modulating cyclosporin A transport

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12 December 2020

Membrane transport proteins associated with drug resistance expressed in human melanoma

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12 December 2020

Tacrolimus oral bioavailability doubles with coadministration of ketoconazole

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12 December 2020

Freeze-thaw and high-voltage discharge allow macromolecule uptake into ileal brush-border vesicles

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12 December 2020

Expression complementary DNA library transfer establishes mrp as a multidrug resistance gene.

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12 December 2020

Secretion of organic anions by hepatocytes: involvement of homologues of the multidrug resistance protein.

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12 December 2020

The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa

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12 December 2020

Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors

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12 December 2020

Possible involvement of multiple P-glycoprotein-mediated efflux systems in the transport of verapamil and other organic cations across rat intestine

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12 December 2020

The secretory intestinal transport of some beta-lactam antibiotics and anionic compounds: a mechanism contributing to poor oral absorption

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12 December 2020

The canalicular multidrug resistance protein, cMRP/MRP2, a novel conjugate export pump expressed in the apical membrane of hepatocytes

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12 December 2020

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport

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12 December 2020

Inhibition of intestinal P-glycoprotein and effects on etoposide absorption.

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12 December 2020

Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

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12 December 2020

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

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12 December 2020

Intracellular pH does not affect drug extrusion by P-glycoprotein

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12 December 2020

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells

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12 December 2020

ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter

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12 December 2020

Transport of a large neutral amino acid (phenylalanine) in a human intestinal epithelial cell line: Caco-2.

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12 December 2020

Active apical secretory efflux of the HIV protease inhibitors saquinavir and ritonavir in Caco-2 cell monolayers

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12 December 2020

Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier

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12 December 2020

Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR.

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12 December 2020

Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells

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12 December 2020

Oral absorption of anti-acquired immune deficiency syndrome nucleoside analogues. 2. Carrier-mediated intestinal transport of stavudine in rat and rabbit preparations

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12 December 2020

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

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12 December 2020

Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein

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12 December 2020

Evidence for a polarized efflux system for peptides in the apical membrane of Caco-2 cells

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12 December 2020

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

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12 December 2020

Lung resistance protein (LRP) expression in human normal tissues in comparison with that of MDR1 and MRP

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12 December 2020

Inhibition of the intestinal digoxin absorption and exsorption by quinidine

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12 December 2020

Identifiers

DOI

10.1023/A:1011971303880

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4 February 2018

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4 February 2018