(Q47732152)

5 February 2018

title

The polyamine-derived amino acid hypusine: its post-translational formation in eIF-5A and its role in cell proliferation (English)

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5 February 2018

author name string

M H Park

1

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5 February 2018

Y A Joe

2

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5 February 2018

K R Kang

3

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5 February 2018

Y B Lee

4

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5 February 2018

E C Wolff

5

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5 February 2018

publication date

1 June 1996

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5 February 2018

published in

Amino Acids

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5 February 2018

volume

10

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5 February 2018

issue

2

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5 February 2018

page(s)

109-121

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5 February 2018

https://scigraph.springernature.com/pub.10.1007/bf00806584

exact match

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cites work

Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF00806584

Changes in eIF-4D hypusine modification or abundance are not correlated with translational repression in HeLa cells

21 January 2018

1 reference

12 December 2020

Hydralazine inhibition of the post-translational hydroxylation of deoxyhypusine, a polyamine-derived amino acid

1 reference

12 December 2020

The biosynthesis of protein-bound hypusine (N epsilon -(4-amino-2-hydroxybutyl)lysine). Lysine as the amino acid precursor and the intermediate role of deoxyhypusine (N epsilon -(4-aminobutyl)lysine)

1 reference

12 December 2020

Induced gene expression of the hypusine-containing protein eukaryotic initiation factor 5A in activated human T lymphocytes

1 reference

12 December 2020

Initiation of mammalian protein synthesis. I. Purification and characterization of seven initiation factors

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12 December 2020

Cloning and expression of human deoxyhypusine synthase cDNA. Structure-function studies with the recombinant enzyme and mutant proteins

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12 December 2020

The active site of deoxyhypusyl hydroxylase: use of catecholpeptides and their component chelator and peptide moieties as molecular probes

1 reference

12 December 2020

Distribution of hypusione, N6(-4amino-2-hydroxybutyl)-2, 6-diaminohexanoic acid, in mammalian organs

1 reference

12 December 2020

Identification of hypusine, an unusual amino acid, in a protein from human lymphocytes and of spermidine as its biosynthetic precursor

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12 December 2020

Identification of the hypusine-containing protein hy+ as translation initiation factor eIF-4D.

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12 December 2020

The HYP2 gene of Saccharomyces cerevisiae is essential for aerobic growth: characterization of different isoforms of the hypusine-containing protein Hyp2p and analysis of gene disruption mutants

1 reference

12 December 2020

Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy

1 reference

12 December 2020

Hypusine: its post-translational formation in eukaryotic initiation factor 5A and its potential role in cellular regulation.

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12 December 2020

The mammalian hypusine-containing protein, eukaryotic initiation factor 4D. Structural homology of this protein from several species

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12 December 2020

Structural features of the eIF-5A precursor required for posttranslational synthesis of deoxyhypusine

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12 December 2020

Is hypusine essential for eukaryotic cell proliferation?

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12 December 2020

Deoxyhypusine hydroxylase from rat testis. Partial purification and characterization

1 reference

12 December 2020

Dissociation of the early antiproliferative action of methylglyoxal bis(guanylhydrazone) from polyamine depletion. A comparison of the effects of DL-alpha-difluromethyl ormithine and methylglyoxal bis(guanylhydrazone) on the growth of human fibrobla

1 reference

12 December 2020

Cleavage of spermidine as the first step in deoxyhypusine synthesis. The role of NAD.

1 reference

12 December 2020

Biosynthetic labeling of hypusine in mammalian cells. Carbon-hydrogen bond fissions revealed by dual labeling

1 reference

12 December 2020

Identification of YHR068w in Saccharomyces cerevisiae chromosome VIII as a gene for deoxyhypusine synthase. Expression and characterization of the enzyme

1 reference

12 December 2020

Hypusine, N6-(4-amino-2-hydroxybutyl)-2,6-diaminohexanoic acid, in tissue proteins of mammals

1 reference

12 December 2020

Posttranslational formation of hypusine in a single major protein occurs generally in growing cells and is associated with activation of lymphocyte growth

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12 December 2020

Regulation of biosynthesis of hypusine in Chinese hamster ovary cells. Evidence for eIF-4D precursor polypeptides.

1 reference

12 December 2020

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12 December 2020

Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation

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12 December 2020

Isolation and identification of alpha-(beta-alanyl)hypusine from bovine brain

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12 December 2020

Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of Chinese hamster ovary cells by guanyl diamines.

1 reference

12 December 2020

Comparison of the activities of variant forms of eIF-4D. The requirement for hypusine or deoxyhypusine.

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12 December 2020

Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein.

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12 December 2020

Inhibition of the G1-S transition of the cell cycle by inhibitors of deoxyhypusine hydroxylation

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12 December 2020

NAD+ stimulated the spermidine-dependent hypusine formation on the 18 kDa protein in cytosolic lysates derived from NB-15 mouse neuroblastoma cells

1 reference

12 December 2020

The biosynthesis of hypusine (N epsilon-(4-amino-2-hydroxybutyl)lysine). Alignment of the butylamine segment and source of the secondary amino nitrogen

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12 December 2020

Hypusine formation in protein by a two-step process in cell lysates

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12 December 2020

Purification and properties of rabbit reticulocyte protein synthesis initiation factors M2Balpha and M2Bbeta

1 reference

12 December 2020

Hypusine, a new amino acid occurring in bovine brain. Isolation and structural determination

1 reference

12 December 2020

Protein synthesis initiation factor eIF-4D. Functional comparison of native and unhypusinated forms of the protein

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12 December 2020

Diamine and Triamine Analogs and Derivatives as Inhibitors of Deoxyhypusine Synthase: Synthesis and Biological Activity

1 reference

12 December 2020

Deoxyhypusine synthase from rat testis: purification and characterization

1 reference

12 December 2020

Effect of initiation factor eIF-5A depletion on protein synthesis and proliferation of Saccharomyces cerevisiae

1 reference

12 December 2020

Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine may be due to hypusine depletion

1 reference

12 December 2020

Purification of deoxyhypusine synthase from Neurospora crassa to homogeneity by substrate elution affinity chromatography

1 reference

12 December 2020

Nomenclature of initiation, elongation and termination factors for translation in eukaryotes. Recommendations 1988. Nomenclature Committee of the International Union of Biochemistry (NC-IUB)

1 reference

12 December 2020

Features of the spermidine-binding site of deoxyhypusine synthase as derived from inhibition studies. Effective inhibition by bis- and mono-guanylated diamines and polyamines.

1 reference

12 December 2020

The essential role of hypusine in eukaryotic translation initiation factor 4D (eIF-4D). Purification of eIF-4D and its precursors and comparison of their activities

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12 December 2020

Purification and characterization of human deoxyhypusine synthase from HeLa cells

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12 December 2020

Isolation and identification of alpha-(gamma-aminobutyryl)-hypusine

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12 December 2020

Identifiers

DOI

10.1007/BF00806584

1 reference

5 February 2018

1 reference

5 February 2018