(Q47740260)

English

A novel defense system of mitochondria in mice and human subjects for preventing expression of mitochondrial dysfunction by pathogenic mutant mtDNAs

scientific article published in November 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

A novel defense system of mitochondria in mice and human subjects for preventing expression of mitochondrial dysfunction by pathogenic mutant mtDNAs (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

human subject research project

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author name string

Kazuto Nakada

1

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

Tomoko Ono

2

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

Jun-Ichi Hayashi

3

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

publication date

1 November 2002

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

2

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

1-2

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

59-70

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

Transcription of the mammalian mitochondrial genome

1 reference

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Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

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Very rare complementation between mitochondria carrying different mitochondrial DNA mutations points to intrinsic genetic autonomy of the organelles in cultured human cells.

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Kearns-Sayre syndrome presenting as renal tubular acidosis

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Two distinct types of mitochondrial DNA segregation in mouse-rat hybrid cells. Stochastic segregation and chromosome-dependent segregation

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Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction

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Human mitochondria and mitochondrial genome function as a single dynamic cellular unit

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Isolation and characterization of mitochondrial DNA-less lines from various mammalian cell lines by application of an anticancer drug, ditercalinium

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Isolation of mitochondrial DNA-less mouse cell lines and their application for trapping mouse synaptosomal mitochondrial DNA with deletion mutations

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Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes

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Nuclear-recessive mutations of factors involved in mitochondrial translation are responsible for age-related respiration deficiency of human skin fibroblasts

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Functional integrity of mitochondrial genomes in human platelets and autopsied brain tissues from elderly patients with Alzheimer's disease

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Molecular Biology of Aging

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Elimination of paternal mitochondrial DNA in intraspecific crosses during early mouse embryogenesis

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Molecular genetic aspects of human mitochondrial disorders

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Mitochondrial DNA--all things bad?

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Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

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Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

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Ageing and mammalian mitochondrial genetics

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Interaction theory of mammalian mitochondria

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Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.

1 reference

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7 January 2021

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Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria

1 reference

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Deletion of mitochondrial DNA in patient with chronic tubulointerstitial nephritis

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Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain

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Mitochondrial DNA deletion: a cause of chronic tubulointerstitial nephropathy

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The interorganellar interaction between distinct human mitochondria with deletion mutant mtDNA from a patient with mitochondrial disease and with HeLa mtDNA

1 reference

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7 January 2021

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Transcomplementation between different types of respiration-deficient mitochondria with different pathogenic mutant mitochondrial DNAs

1 reference

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Mitochondrial genetics: a paradigm for aging and degenerative diseases?

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Mitochondrial diseases in man and mouse

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Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.

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Mice with only rat mtDNA are required as models of mitochondrial diseases

1 reference

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Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles

1 reference

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Identifiers

10.1016/S1567-7249(02)00007-7

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/16120309

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