(Q47778761)

5 February 2018

title

The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution (English)

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5 February 2018

author name string

Shi-Ying Cai

1

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5 February 2018

Liangshi Xiong

2

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5 February 2018

Charles G Wray

3

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5 February 2018

Nazzareno Ballatori

4

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5 February 2018

James L Boyer

5

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5 February 2018

publication date

13 June 2007

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5 February 2018

American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

published in

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volume

293

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5 February 2018

issue

3

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page(s)

R1400-9

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5 February 2018

Parallel Metropolis coupled Markov chain Monte Carlo for Bayesian phylogenetic inference

cites work

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

21 January 2018

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Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Evolution of hormone-receptor complexity by molecular exploitation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Nuclear receptors RXRalpha:RARalpha are repressors for human MRP3 expression

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

The Farnesoid X receptor: a molecular link between bile acid and lipid and glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Ligand binding was acquired during evolution of nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Identification of a nuclear receptor that is activated by farnesol metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters

21 January 2018

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The rapid generation of mutation data matrices from protein sequences

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

The first completed genome sequence from a teleost fish (Fugu rubripes) adds significant diversity to the nuclear receptor superfamily

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Identification of a nuclear receptor for bile acids

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Structural basis for bile acid binding and activation of the nuclear receptor FXR

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol

21 January 2018

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Fatty acid distribution in muscle, liver, and gonads of rays (Dasyatis marmorata, Rhinobatos cemiculus, and Rhinoptera marginata) from the East Tropical Atlantic Ocean

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

MrBayes 3: Bayesian phylogenetic inference under mixed models

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

FOR, a novel orphan nuclear receptor related to farnesoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

The nuclear hormone receptor farnesoid X receptor (FXR) is activated by androsterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

Polyunsaturated fatty acids are FXR ligands and differentially regulate expression of FXR targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00781.2006

10.1152/AJPREGU.00781.2006

21 January 2018

Identifiers

DOI

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5 February 2018

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5 February 2018