(Q47779125)

5 February 2018

title

Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update (English)

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5 February 2018

author name string

Ekarat Jantratid

1

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5 February 2018

Niels Janssen

2

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5 February 2018

Christos Reppas

3

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5 February 2018

Jennifer B Dressman

4

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5 February 2018

publication date

11 April 2008

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5 February 2018

published in

Pharmaceutical Research

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5 February 2018

volume

25

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5 February 2018

issue

7

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5 February 2018

page(s)

1663-1676

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5 February 2018

Drug solubilization behavior during in vitro digestion of suspension formulations of poorly water-soluble drugs in triglyceride lipids

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12 December 2020

Wetting characteristics of media emulating gastric fluids

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12 December 2020

Upper gastrointestinal (GI) pH in young, healthy men and women.

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Kinetics of release from enteric-coated tablets.

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Dissolution of ionizable water-insoluble drugs: the combined effect of pH and surfactant

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Comparative response of exocrine pancreatic secretion following a test meal and secretin-pancreozymin stimulation

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Albendazole generics--a comparative in vitro study

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Canine intestinal contents vs. simulated media for the assessment of solubility of two weak bases in the human small intestinal contents.

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12 December 2020

Influence of dissolution media composition on drug release and in-vitro/in-vivo correlation for paracetamol matrix tablets prepared with novel carbomer polymers

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Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds

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12 December 2020

Estimation of the increase in solubility of drugs as a function of bile salt concentration.

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12 December 2020

Effect of chloride ion on dissolution of different salt forms of haloperidol, a model basic drug

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12 December 2020

Drug binding and solubility in milk

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12 December 2020

Comparative study of secretin and Lundh tests

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12 December 2020

Dissolution Kinetics of Carboxylic Acids II: Effect of Buffers

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12 December 2020

Predicting pharmacokinetic food effects using biorelevant solubility media and physiologically based modelling.

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12 December 2020

Characterization of the human upper gastrointestinal contents under conditions simulating bioavailability/bioequivalence studies.

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12 December 2020

In vitro dissolution studies of sodium diclofenac granules coated with Eudragit L-30D-55 by fluidized-bed system.

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12 December 2020

The influence of buffer species and strength on diltiazem HCl release from beads coated with the aqueous cationic polymer dispersions, Eudragit RS, RL 30D.

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12 December 2020

Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption

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12 December 2020

Wetting properties of bile salt solutions and dissolution media.

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12 December 2020

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

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12 December 2020

Upper gastrointestinal pH in seventy-nine healthy, elderly, North American men and women.

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12 December 2020

Physiochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH.

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12 December 2020

Drug, meal and formulation interactions influencing drug absorption after oral administration. Clinical implications

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12 December 2020

Designing biorelevant dissolution tests for lipid formulations: case example--lipid suspension of RZ-50.

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12 December 2020

In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs

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12 December 2020

Lipases and lipolysis in the human digestive tract: where do we stand?

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12 December 2020

Dissolution media simulating the intralumenal composition of the small intestine: physiological issues and practical aspects.

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12 December 2020

pH and the Henderson-Hasselbalch equation

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12 December 2020

Development of an in vitro/in vivo correlation for lipid formulations of EMD 50733, a poorly soluble, lipophilic drug substance

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12 December 2020

Biorelevant dissolution media as a predictive tool for glyburide a class II drug.

1 reference

12 December 2020

The specific activities of human digestive lipases measured from the in vivo and in vitro lipolysis of test meals

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12 December 2020

Enteric coated HPMC capsules designed to achieve intestinal targeting

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12 December 2020

Is bicarbonate buffer suitable as a dissolution medium?

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12 December 2020

Forecasting the oral absorption behavior of poorly soluble weak bases using solubility and dissolution studies in biorelevant media

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12 December 2020

A dynamic in vitro lipolysis model

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12 December 2020

In vitro assessment of oral lipid based formulations

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12 December 2020

Sustained-release from layered matrix system comprising chitosan and xanthan gum.

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12 December 2020

Effect of temperature and fat content on the solubility of hydrochlorothiazide and chlorothiazide in milk

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12 December 2020

Estimation of intragastric solubility of drugs: in what medium?

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12 December 2020

Solubilization and dissolution of insoluble weak acid, ketoprofen: effects of pH combined with surfactant

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12 December 2020

Investigation of solubility and dissolution of a free base and two different salt forms as a function of pH.

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12 December 2020

Canine versus in vitro data for predicting input profiles of L-sulpiride after oral administration

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12 December 2020

A new 5-aminosalicylic acid multi-unit dosage form for the therapy of ulcerative colitis

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12 December 2020

Drug solubilization behavior during in vitro digestion of simple triglyceride lipid solution formulations

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12 December 2020

Digestion and absorption of 2 fat emulsions with different droplet sizes in the human digestive tract

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12 December 2020

Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides

1 reference

12 December 2020

Effect of temperature and fat content on the binding of hydrochlorothiazide and chlorothiazide to milk

1 reference

12 December 2020

Media to simulate the postprandial stomach I. Matching the physicochemical characteristics of standard breakfasts.

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12 December 2020

Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system.

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12 December 2020

Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs

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12 December 2020

In vivo in vitro correlations for a poorly soluble drug, danazol, using the flow-through dissolution method with biorelevant dissolution media

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12 December 2020

Biorelevant dissolution testing to predict the plasma profile of lipophilic drugs after oral administration

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12 December 2020

Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings

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12 December 2020

Influence of an enteric polymer on drug release rates of theophylline from pellets coated with Eudragit RS 30D.

1 reference

12 December 2020

Dissolution Kinetics of Carboxylic Acids I: Effect of pH Under Unbuffered Conditions

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12 December 2020

Physicochemical characteristics of emulsions during fat digestion in human stomach and duodenum.

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12 December 2020

Wetting behavior of bile salt-lipid dispersions and dissolution media patterned after intestinal fluids

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12 December 2020

Eudragit RS 100 microparticles containing 2-hydroxypropyl-beta-cyclodextrin and glutathione: physicochemical characterization, drug release and transport studies

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12 December 2020

Forecasting the in vivo performance of four low solubility drugs from their in vitro dissolution data

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12 December 2020

Analysis of the solubilization of steroids by bile salt micelles

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12 December 2020

A dynamic in vitro lipolysis model. II: Evaluation of the model

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12 December 2020

Dissolution testing as a prognostic tool for oral drug absorption: immediate release dosage forms

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12 December 2020

An investigation of the disintegration of tablets in biorelevant media

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12 December 2020

Effects of food on drug absorption

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12 December 2020

Factorial analysis of the influence of dissolution medium on drug release from carrageenan-diltiazem complexes

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12 December 2020

10.1007/S11095-008-9569-4

Identifiers

DOI

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5 February 2018

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5 February 2018