(Q47779246)

5 February 2018

title

Phosphonate and bisphosphonate analogues of farnesyl pyrophosphate as potential inhibitors of farnesyl protein transferase (English)

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5 February 2018

author name string

Holstein SA

1

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5 February 2018

Cermak DM

2

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5 February 2018

Wiemer DF

3

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5 February 2018

Lewis K

4

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5 February 2018

Hohl RJ

5

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5 February 2018

language of work or name

English

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publication date

1 June 1998

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5 February 2018

Bioorganic & Medicinal Chemistry

published in

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5 February 2018

volume

6

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5 February 2018

issue

6

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5 February 2018

page(s)

687-694

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5 February 2018

Function and regulation of ras.

cites work

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7 January 2021

Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses

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Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules

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All ras proteins are polyisoprenylated but only some are palmitoylated

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Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.

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Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

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7 January 2021

A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and Ras processing

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7 January 2021

Phosphinyl acid-based bisubstrate analog inhibitors of Ras farnesyl protein transferase

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7 January 2021

Actinoplanic Acid A: A Macrocyclic Polycarboxylic Acid Which Is a Potent Inhibitor of Ras Farnesyl-Protein Transferase

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7 January 2021

Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase

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7 January 2021

Inhibition of farnesyl-protein transferase by gliotoxin and acetylgliotoxin

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7 January 2021

Preussomerins and Deoxypreussomerins: Novel Inhibitors of Ras Farnesyl-Protein Transferase

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7 January 2021

Steady-state kinetic mechanism of Ras farnesyl:protein transferase

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7 January 2021

Farnesyl-derived inhibitors of ras farnesyl transferase

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7 January 2021

Farnesyl diphosphate-based inhibitors of Ras farnesyl protein transferase

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7 January 2021

Cuprate-Mediated Synthesis and Biological Evaluation of Cyclopropyl- and tert-Butylfarnesyl Diphosphate Analogs

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7 January 2021

A rapid and convenient filter-binding assay for ras p21 processing enzyme farnesyltransferase

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7 January 2021

Stereochemistry-dependent inhibition of RAS farnesylation by farnesyl phosphonic acids

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7 January 2021

Protein farnesyltransferase: measurement of enzymatic activity in 96-well format using TopCount microplate scintillation counting technology

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7 January 2021

Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

1 reference

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7 January 2021

10.1016/S0968-0896(98)00034-0

Identifiers

DOI

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5 February 2018

1 reference

5 February 2018