(Q47797859)

17 June 2018

editorial

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title

What is hydroxynorketamine and what can it bring to neurotherapeutics? (English)

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17 June 2018

author

Michel Bernier

4

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17 June 2018

author name string

Nagendra S Singh

1

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17 June 2018

Carlos A Zarate

2

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17 June 2018

Ruin Moaddel

3

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17 June 2018

Irving W Wainer

5

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17 June 2018

publication date

1 November 2014

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17 June 2018

Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

published in

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17 June 2018

volume

14

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17 June 2018

issue

11

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17 June 2018

page(s)

1239-1242

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17 June 2018

(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.

cites work

1 reference

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To use or not to use: an update on licit and illicit ketamine use

18 June 2018

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Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells

18 June 2018

1 reference

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Activation of mammalian target of rapamycin and synaptogenesis: role in the actions of rapid-acting antidepressants

18 June 2018

1 reference

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Gabapentin and (S)-pregabalin decrease intracellular D-serine concentrations in PC-12 cells

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Sub-anesthetic concentrations of (R,S)-ketamine metabolites inhibit acetylcholine-evoked currents in α7 nicotinic acetylcholine receptors.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Stereoselective and regiospecific hydroxylation of ketamine and norketamine

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression

18 June 2018

1 reference

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Advances in translational neuropathic research: example of enantioselective pharmacokinetic-pharmacodynamic modeling of ketamine-induced pain relief in complex regional pain syndrome

18 June 2018

1 reference

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Inhibition of human serine racemase, an emerging target for medicinal chemistry.

18 June 2018

1 reference

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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

18 June 2018

1 reference

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Taming the ketamine tiger. 1965.

18 June 2018

1 reference

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Glutamate-based antidepressants: 20 years on.

18 June 2018

1 reference

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D-serine regulation: a possible therapeutic approach for central nervous diseases and chronic pain

18 June 2018

1 reference

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D-amino acids in the brain: D-serine in neurotransmission and neurodegeneration.

18 June 2018

1 reference

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A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression

18 June 2018

1 reference

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PHARMACOLOGIC EFFECTS OF CI-581, A NEW DISSOCIATIVE ANESTHETIC, IN MAN.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Direct calcium binding results in activation of brain serine racemase

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Antidepressant effects of ketamine in depressed patients

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Intramuscular ketamine for pediatric sedation in the emergency department: safety profile in 1,022 cases

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Studies on the biotransformation of ketamine. 1-Identification of metabolites produced in vitro from rat liver microsomal preparations.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Comparative pharmacology in the rat of ketamine and its two principal metabolites, norketamine and (Z)-6-hydroxynorketamine.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Ketamine as an antidepresessant: a brief research history

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Ketamine: new uses for an old drug?

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Two case studies of patients with major depressive disorder given low-dose (subanesthetic) ketamine infusions

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5990010

Neuronal D-serine and glycine release via the Asc-1 transporter regulates NMDA receptor-dependent synaptic activity

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25331415

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1586/14737175.2014.971760

1 reference

17 June 2018

PMC publication ID

5990010

1 reference

17 June 2018

PubMed publication ID

25331415

1 reference

17 June 2018