(Q47817973)

5 February 2018

review article

1 reference

title

TGF-beta signaling, Smads, and tumor suppressors (English)

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5 February 2018

author name string

Padgett RW

series ordinal

1

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5 February 2018

Das P

series ordinal

2

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5 February 2018

Krishna S

series ordinal

3

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5 February 2018

language of work or name

English

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publication date

1 May 1998

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5 February 2018

published in

BioEssays

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5 February 2018

volume

20

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5 February 2018

issue

5

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5 February 2018

page(s)

382-390

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5 February 2018

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues

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Expression cloning of an activin receptor, a predicted transmembrane serine kinase

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Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor

21 January 2018

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Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

21 January 2018

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Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells

21 January 2018

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Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-beta

21 January 2018

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Decapentaplegic: a gene complex affecting morphogenesis in Drosophila melanogaster.

21 January 2018

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The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo

21 January 2018

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A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-beta family.

21 January 2018

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Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo

21 January 2018

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Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals

21 January 2018

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The screw gene encodes a ubiquitously expressed member of the TGF-beta family required for specification of dorsal cell fates in the Drosophila embryo

21 January 2018

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Drosophila 60A gene, another transforming growth factor beta family member, is closely related to human bone morphogenetic proteins

21 January 2018

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Sequence, biochemical characterization, and developmental expression of a new member of the TGF-beta superfamily in Drosophila melanogaster

21 January 2018

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Two distinct transmembrane serine/threonine kinases from Drosophila melanogaster form an activin receptor complex

21 January 2018

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An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo

21 January 2018

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daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase

21 January 2018

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The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development

21 January 2018

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Control of C. elegans larval development by neuronal expression of a TGF-beta homolog

21 January 2018

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Novel regulators of bone formation: molecular clones and activities

21 January 2018

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The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1.

21 January 2018

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Molecular cloning of cDNA for human complement component C1s. The complete amino acid sequence

21 January 2018

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Two domains of the tolloid protein contribute to its unusual genetic interaction with decapentaplegic.

21 January 2018

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Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

21 January 2018

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Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

21 January 2018

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Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction

21 January 2018

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Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4.

21 January 2018

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The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4

21 January 2018

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The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor.

21 January 2018

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The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-beta superfamily

21 January 2018

1 reference

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Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic

21 January 2018

1 reference

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Characterization and relationship of Dpp receptors encoded by the saxophone and thick veins genes in Drosophila.

21 January 2018

1 reference

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Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291521-1878%28199805%2920%3A5%3C382%3A%3AAID-BIES5%3E3.0.CO%3B2-Q

Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF beta receptor family

21 January 2018

1 reference

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Identification of a Drosophila activin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291521-1878%28199805%2920%3A5%3C382%3A%3AAID-BIES5%3E3.0.CO%3B2-Q

Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors

21 January 2018

1 reference

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Chimeric granulocyte/macrophage colony-stimulating factor/transforming growth factor-beta (TGF-beta) receptors define a model system for investigating the role of homomeric and heteromeric receptors in TGF-beta signaling

21 January 2018

1 reference

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Nomenclature: vertebrate mediators of TGFbeta family signals

21 January 2018

1 reference

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21 January 2018

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

1 reference

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The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

21 January 2018

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

21 January 2018

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MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

21 January 2018

1 reference

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Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1

21 January 2018

1 reference

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A human Mad protein acting as a BMP-regulated transcriptional activator

21 January 2018

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Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth

21 January 2018

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Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

21 January 2018

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A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291521-1878%28199805%2920%3A5%3C382%3A%3AAID-BIES5%3E3.0.CO%3B2-Q

21 January 2018

1 reference

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A transcriptional partner for MAD proteins in TGF-beta signalling

21 January 2018

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Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

21 January 2018

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Tumor suppressor activity of the TGF-beta pathway in human cancers

21 January 2018

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Mad-related genes in the human

21 January 2018

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A structural basis for mutational inactivation of the tumour suppressor Smad4

21 January 2018

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Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

21 January 2018

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Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

21 January 2018

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Smad6 inhibits signalling by the TGF-beta superfamily

21 January 2018

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

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Daughters against dpp modulates dpp organizing activity in Drosophila wing development

21 January 2018

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Production of a DPP activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteins

21 January 2018

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Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity

21 January 2018

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The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway

21 January 2018

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Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

21 January 2018

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Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

21 January 2018

1 reference

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10.1002/(SICI)1521-1878(199805)20:5<382::AID-BIES5>3.0.CO;2-Q

21 January 2018

Identifiers

DOI

1 reference

5 February 2018

1 reference

5 February 2018