(Q47851505)

6 February 2018

review article

1 reference

title

Engineering protein kinases with distinct nucleotide specificities and inhibitor sensitivities by mutation of a single amino acid. (English)

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6 February 2018

author name string

P Cohen

series ordinal

1

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6 February 2018

M Goedert

series ordinal

2

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6 February 2018

publication date

1 July 1998

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6 February 2018

published in

Chemistry and Biology

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6 February 2018

volume

5

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6 February 2018

issue

7

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6 February 2018

page(s)

R161-4

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6 February 2018

Engineering Src family protein kinases with unnatural nucleotide specificity

cites work

1 reference

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7 January 2021

Design of allele-specific inhibitors to probe protein kinase signaling

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7 January 2021

Crystal structure of the Src family tyrosine kinase Hck

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7 January 2021

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990068-0

7 January 2021

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990068-0

7 January 2021

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

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https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990068-0

7 January 2021

The search for physiological substrates of MAP and SAP kinases in mammalian cells

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https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990068-0

7 January 2021

Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990068-0

7 January 2021

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990068-0

7 January 2021

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990068-0

7 January 2021

Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990068-0

7 January 2021

Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990068-0

7 January 2021

10.1016/S1074-5521(98)90068-0

Identifiers

DOI

1 reference

6 February 2018

PubMed ID

9662509

1 reference

6 February 2018