(Q47851514)

6 February 2018

title

TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins (English)

1 reference

6 February 2018

author name string

B R Stockwell

series ordinal

1

1 reference

6 February 2018

S L Schreiber

series ordinal

2

1 reference

6 February 2018

publication date

1 July 1998

1 reference

6 February 2018

number of pages

11

1 reference

inferred from page(s)

published in

Chemistry and Biology

1 reference

6 February 2018

volume

5

1 reference

6 February 2018

issue

7

1 reference

6 February 2018

page(s)

385-395

1 reference

6 February 2018

Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

1 reference

7 January 2021

Signal transduction by members of the transforming growth factor-beta superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Smad6 inhibits signalling by the TGF-beta superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

A transcriptional partner for MAD proteins in TGF-beta signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Smad4 and FAST-1 in the assembly of activin-responsive factor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Interaction of transforming growth factor-beta receptor I with farnesyl-protein transferase-alpha in yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Cloning of a novel type II serine/threonine kinase receptor through interaction with the type I transforming growth factor-beta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Characterization of the Interaction of FKBP12 with the Transforming Growth Factor-β Type I Receptorin Vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

FKBP-12 recognition is dispensable for signal generation by type I transforming growth factor-beta receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Mechanism of TGFbeta receptor inhibition by FKBP12

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Probing the role of homomeric and heteromeric receptor interactions in TGF-beta signaling using small molecule dimerizers

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Controlling signal transduction with synthetic ligands

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Transforming growth factor-beta (TGF-beta)-induced down-regulation of cyclin A expression requires a functional TGF-beta receptor complex. Characterization of chimeric and truncated type I and type II receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Mechanism of activation of the TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

A transforming growth factor beta type I receptor that signals to activate gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2898%2990072-2

7 January 2021

10.1016/S1074-5521(98)90072-2

Identifiers

DOI

1 reference

6 February 2018

1 reference

6 February 2018