(Q47878245)

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New malaria vaccine candidates based on the Plasmodium vivax Merozoite Surface Protein-1 and the TLR-5 agonist Salmonella Typhimurium FliC flagellin.

scientific article published on 18 September 2008

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18804504%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

New malaria vaccine candidates based on the Plasmodium vivax Merozoite Surface Protein-1 and the TLR-5 agonist Salmonella Typhimurium FliC flagellin (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18804504%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Plasmodium vivax

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toll-like receptor

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1 reference

based on heuristic

inferred from title

malaria vaccine

1 reference

based on heuristic

inferred from title

Salmonella Typhimurium

1 reference

based on heuristic

inferred from title

Daniel Youssef Bargieri

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18804504%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Daniela Santoro Rosa

2

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14 January 2020

Luis Carlos de Souza Ferreira

9

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14 January 2020

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Catarina J M Braga

3

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14 January 2020

Bruna O Carvalho

4

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14 January 2020

Fabio T M Costa

5

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14 January 2020

Noeli Maria Espíndola

6

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14 January 2020

Adelaide José Vaz

7

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14 January 2020

Irene S Soares

8

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14 January 2020

Mauricio M Rodrigues

10

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14 January 2020

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18 September 2008

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14 January 2020

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14 January 2020

26

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14 January 2020

48

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14 January 2020

6132-6142

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14 January 2020

Vivax malaria: neglected and not benign

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Neglect of Plasmodium vivax malaria

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Construction and immunogenicity of DNA vaccine plasmids encoding four Plasmodium vivax candidate vaccine antigens

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The use of transgenic Plasmodium berghei expressing the Plasmodium vivax antigen P25 to determine the transmission-blocking activity of sera from malaria vaccine trials

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Transmission-blocking activity induced by malaria vaccine candidates Pfs25/Pvs25 is a direct and predictable function of antibody titer

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Immunogenicity in rhesus of the Plasmodium vivax mosquito stage antigen Pvs25H with Alhydrogel and Montanide ISA 720.

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An update on the search for a Plasmodium vivax vaccine

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Antigenicity, immunogenicity, and protective efficacy of Plasmodium vivax MSP1 PV200l: a potential malaria vaccine subunit

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Purification, characterization, and immunogenicity of a disulfide cross-linked Plasmodium vivax vaccine candidate antigen, merozoite surface protein 1, expressed in Escherichia coli

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Comparison of immunogenicities of recombinant Plasmodium vivax merozoite surface protein 1 19- and 42-kiloDalton fragments expressed in Escherichia coli

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Merozoite surface protein 1 of Plasmodium vivax induces a protective response against Plasmodium cynomolgi challenge in rhesus monkeys

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Immunogenicity of Plasmodium vivax combination subunit vaccine formulated with human compatible adjuvants in mice

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Immunogenicity and protective efficacy of recombinant vaccine based on the receptor-binding domain of the Plasmodium vivax Duffy binding protein in Aotus monkeys

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Plasmodium vivax invasion of human erythrocytes inhibited by antibodies directed against the Duffy binding protein

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Targeting the Plasmodium vivax Duffy-binding protein.

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Immunogenicity of Plasmodium vivax merozoite surface protein-9 recombinant proteins expressed in E. coli.

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The antigenicity of a Plasmodium vivax reticulocyte binding protein-1 (PvRBP1) recombinant fragment in humans and its immunogenicity and protection studies in Aotus monkeys.

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A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.

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Functional conservation of the malaria vaccine antigen MSP-119across distantly related Plasmodium species

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Comparison of the immunogenic properties of recombinant proteins representing the Plasmodium vivax vaccine candidate MSP1(19) expressed in distinct bacterial vectors

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7 January 2021

Serological detection of Plasmodium vivax malaria using recombinant proteins corresponding to the 19-kDa C-terminal region of the merozoite surface protein-1

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The pan HLA DR-binding epitope improves adjuvant-assisted immunization with a recombinant protein containing a malaria vaccine candidate

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Adjuvant requirement for successful immunization with recombinant derivatives of Plasmodium vivax merozoite surface protein-1 delivered via the intranasal route

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Immunogenicity of a recombinant protein containing the Plasmodium vivax vaccine candidate MSP1(19) and two human CD4+ T-cell epitopes administered to non-human primates (Callithrix jacchus jacchus).

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Innate immune recognition

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Pathogen recognition and innate immunity

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Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

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Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility

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Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

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A bacterial flagellin, Vibrio vulnificus FlaB, has a strong mucosal adjuvant activity to induce protective immunity

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Cellular mechanisms of the adjuvant activity of the flagellin component FljB of Salmonella enterica Serovar Typhimurium to potentiate mucosal and systemic responses

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Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis

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Flagellin fusion proteins as adjuvants or vaccines induce specific immune responses

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Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity

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The attenuated phenotype of a Salmonella typhimurium flgM mutant is related to expression of FliC flagellin

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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

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Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

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Identification of a novel negative role of flagellin in regulating IL-10 production.

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based on heuristic

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Passive immunization with antibodies against three distinct epitopes on Plasmodium yoelii merozoite surface protein 1 suppresses parasitemia

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Baculovirus merozoite surface protein 1 C-terminal recombinant antigens are highly protective in a natural primate model for human Plasmodium vivax malaria

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based on heuristic

inferred from DOI database lookup

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