(Q47900941)

6 February 2018

title

Lack of seipin in neurons results in anxiety- and depression-like behaviors via down regulation of PPARγ. (English)

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6 February 2018

author

Jiawei Liao

4

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6 February 2018

author name string

Libin Zhou

1

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6 February 2018

Jun Yin

2

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6 February 2018

Conghui Wang

3

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6 February 2018

George Liu

5

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6 February 2018

Ling Chen

6

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6 February 2018

publication date

20 March 2014

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6 February 2018

published in

Human Molecular Genetics

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6 February 2018

volume

23

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6 February 2018

issue

15

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6 February 2018

page(s)

4094-4102

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6 February 2018

Phenotypic and genetic heterogeneity in congenital generalized lipodystrophy

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Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13.

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Heterozygous missense mutations in BSCL2 are associated with distal hereditary motor neuropathy and Silver syndrome

21 January 2018

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Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

21 January 2018

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The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology

21 January 2018

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The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation

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Seipin ablation in mice results in severe generalized lipodystrophy.

21 January 2018

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A role for phosphatidic acid in the formation of "supersized" lipid droplets

21 January 2018

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Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis

21 January 2018

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Characterization of seipin/BSCL2, a protein associated with spastic paraplegia 17.

21 January 2018

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Seipin: a mysterious protein

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Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy

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Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation

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1 reference

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The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation

21 January 2018

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21 January 2018

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PPAR-gamma Pro12Ala genotype and risk of cognitive decline in elders

21 January 2018

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Antidepressant-like effect of pioglitazone in the forced swimming test in mice: the role of PPAR-gamma receptor and nitric oxide pathway.

21 January 2018

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Seipin regulates excitatory synaptic transmission in cortical neurons.

21 January 2018

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A role for central nervous system PPAR-γ in the regulation of energy balance

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

21 January 2018

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Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

21 January 2018

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Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal

21 January 2018

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PPARgamma-mediated advanced glycation end products regulation of neural stem cells.

21 January 2018

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Peroxisome proliferator-activated receptor gamma-mediated regulation of neural stem cell proliferation and differentiation

21 January 2018

1 reference

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PPARγ activation prevents impairments in spatial memory and neurogenesis following transient illness

21 January 2018

1 reference

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Neuroprotective effects of KR-62980, a new PPARγ agonist, against chemical ischemia-reperfusion in SK-N-SH cells

21 January 2018

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21 January 2018

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21 January 2018

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Estrogen improves vascular function via peroxisome-proliferator-activated-receptor-γ.

21 January 2018

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Gonadal hormone modulation of neurogenesis in the dentate gyrus of adult male and female rodents.

21 January 2018

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Estradiol enhances neurogenesis in the dentate gyri of adult male meadow voles by increasing the survival of young granule neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU126

Motor neuron degeneration in a mouse model of seipinopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU126

Increase of anteroventral periventricular kisspeptin neurons and generation of E2-induced LH-surge system in male rats exposed perinatally to environmental dose of bisphenol-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU126

Hippocampal nitric oxide contributes to sex difference in affective behaviors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU126

NMDA receptor involvement in antidepressant-like effect of pioglitazone in the forced swimming test in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU126

Icariin enhances neuronal survival after oxygen and glucose deprivation by increasing SIRT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU126

N88S seipin mutant transgenic mice develop features of seipinopathy/BSCL2-related motor neuron disease via endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU126

Membrane topology of the human seipin protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU126

21 January 2018

Identifiers

DOI

10.1093/HMG/DDU126

1 reference

6 February 2018

PubMed ID

24651066

1 reference

6 February 2018