(Q47903001)

6 February 2018

title

Triplet repeat expansion generated by DNA slippage is suppressed by human flap endonuclease 1. (English)

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6 February 2018

author name string

Bethany L Ruggiero

series ordinal

1

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6 February 2018

Michael D Topal

series ordinal

2

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6 February 2018

language of work or name

English

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publication date

22 March 2004

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6 February 2018

Journal of Biological Chemistry

published in

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6 February 2018

volume

279

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6 February 2018

issue

22

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6 February 2018

page(s)

23088-23097

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6 February 2018

Expansion explosion: new clues to the pathogenesis of repeat expansion neurodegenerative diseases

cites work

1 reference

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Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday

21 January 2018

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Length of uninterrupted CGG repeats determines instability in the FMR1 gene

21 January 2018

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Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli.

21 January 2018

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Deoxyribonuclease IV: a new exonuclease from mammalian tissues

21 January 2018

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Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA.

21 January 2018

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Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion

21 January 2018

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RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

21 January 2018

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Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression

21 January 2018

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Trinucleotide repeats: mechanisms and pathophysiology

21 January 2018

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The "flap" endonuclease gene FEN1 is excluded as a candidate gene implicated in the CAG repeat expansion underlying Huntington disease

21 January 2018

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The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair

21 January 2018

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Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats

21 January 2018

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DNA ligase I competes with FEN1 to expand repetitive DNA sequences in vitro

21 January 2018

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Calf 5' to 3' exo/endonuclease must slide from a 5' end of the substrate to perform structure-specific cleavage

21 January 2018

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DNA structural elements required for FEN-1 binding

21 January 2018

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Hairpin formation in Friedreich's ataxia triplet repeat expansion.

21 January 2018

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Molecular basis of Friedreich ataxia

21 January 2018

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Trinucleotide repeats that expand in human disease form hairpin structures in vitro

21 January 2018

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Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich's ataxia

21 January 2018

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Triplet repeats form secondary structures that escape DNA repair in yeast

21 January 2018

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Molecular cloning and high-level expression of human polymerase beta cDNA and comparison of the purified recombinant human and rat enzymes

21 January 2018

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Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism

21 January 2018

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FEN1 stimulation of DNA polymerase beta mediates an excision step in mammalian long patch base excision repair.

21 January 2018

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21 January 2018

DNA replication fidelity

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Cryptic and polar variation of the fragile X repeat could result in predisposing normal alleles.

21 January 2018

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Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome

21 January 2018

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Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

21 January 2018

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THE ACCOMMODATION OF NONCOMPLEMENTARY BASES IN HELICAL POLYRIBONUCLEOTIDES AND DEOXYRIBONUCLEIC ACIDS.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M313170200

21 January 2018

Identifiers

DOI

10.1074/JBC.M313170200

1 reference

6 February 2018

PubMed ID

15037629

1 reference

6 February 2018