(Q47905309)

6 February 2018

title

Medicine. Avoiding unintended toxicity. (English)

1 reference

6 February 2018

author

Thomas Kukar

series ordinal

2

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6 February 2018

author name string

Todd E Golde

series ordinal

1

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6 February 2018

language of work or name

English

0 references

publication date

1 May 2009

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6 February 2018

published in

Science

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6 February 2018

volume

324

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6 February 2018

issue

5927

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6 February 2018

page(s)

603-604

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6 February 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

Disease modifying therapy for AD?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

beta-Secretase as a therapeutic target for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

Identification of distinct gamma-secretase complexes with different APH-1 variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

Discovery of begacestat, a Notch-1-sparing gamma-secretase inhibitor for the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

Substrate-targeting gamma-secretase modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

Rational targeting of Notch signaling in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174267

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1174267

1 reference

6 February 2018

PubMed ID

19407192

1 reference

6 February 2018