(Q47920047)

6 February 2018

title

Impaired primary immune response in type-1 diabetes. Functional impairment at the level of APCs and T-cells (English)

1 reference

https://api.crossref.org/works/10.1016/S0008-8749(03)00043-1

1 January 2024

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12742378

1 January 2024

1 reference

https://api.crossref.org/works/10.1016/S0008-8749(03)00043-1

1 January 2024

author name string

Martin Spatz

1

1 reference

6 February 2018

Nicole Eibl

2

1 reference

6 February 2018

Sandra Hink

3

1 reference

6 February 2018

Guntram Schernthaner

7

1 reference

6 February 2018

Hermann M. Wolf

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12742378

1 January 2024

Gottfried F. Fischer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12742378

1 January 2024

Wolfgang R. Mayr

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12742378

1 January 2024

Martha M. Eibl

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12742378

1 January 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12742378

1 January 2024

publication date

1 January 2003

1 reference

6 February 2018

full work available at URL

https://api.elsevier.com/content/article/PII:S0008874903000431?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0008-8749(03)00043-1

https://api.elsevier.com/content/article/PII:S0008874903000431?httpAccept=text/plain

1 January 2024

1 reference

https://api.crossref.org/works/10.1016/S0008-8749(03)00043-1

1 January 2024

1 reference

6 February 2018

volume

221

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6 February 2018

issue

1

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6 February 2018

page(s)

15-26

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6 February 2018

Impaired primary immune response in type-1 diabetes: results from a controlled vaccination study

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Diabetes in identical twins. A study of 200 pairs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Beta 57-Asp plays an essential role in the unique SDS stability of HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC allele associated with protection from insulin-dependent diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Defective T cell receptor/CD3 complex signaling in human type I diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Constitutive impaired TCR/CD3-mediated activation of T cells in IDDM patients co-exist with normal co-stimulation pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Specific deficiency of p56lck expression in T lymphocytes from type 1 diabetic patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Negative selection of human monocytes using magnetic particles covered by anti-lymphocyte antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Immune response to the herpes simplex type 1 regulatory proteins ICP8 and VP16 in infected persons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young no

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Structural intermediates in the reactions of antigenic peptides with MHC molecules.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Identification of two distinct properties of class II major histocompatibility complex-associated peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Regulation of T and B cell responses by modulating interactions between CD28/CTLA4 and their ligands, CD80 and CD86.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

The microbial product lipopolysaccharide confers diabetogenic potential on the T cell repertoire of BDC2.5/NOD mice: implications for the etiology of autoimmune diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Biochemical characterization of the human diabetes-associated HLA-DQ8 allelic product: similarity to the major histocompatibility complex class II I-A(g)7 protein of non-obese diabetic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Isolation, culture, and characterisation of MHC class II-positive microvascular endothelial cells from the human heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Integrins: versatility, modulation, and signaling in cell adhesion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

From TCR Engagement to T Cell Activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

CD28/B7 system of T cell costimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

The emerging role of CTLA-4 as an immune attenuator

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

CTLA-4 in autoimmune diseases--a general susceptibility gene to autoimmunity?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Tolerance to islet autoantigens in type 1 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Transforming growth factor-beta 1 (TGF-beta1)-mediated inhibition of glial cell proliferation and down-regulation of intercellular adhesion molecule-1 (ICAM-1) are interrupted by interferon-gamma (IFN-gamma)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Immunosuppressive and anti-inflammatory properties of interleukin 10.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

IL-10 is necessary and sufficient for autoimmune diabetes in conjunction with NOD MHC homozygosity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Innate immune recognition: mechanisms and pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Interleukin-6 and its receptor in autoimmunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

A polymorphism in the promoter region of the gene for interleukin-6 is associated with susceptibility to type 1 diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Elevated levels of interleukin-6 in young adults with type 1 diabetes without clinical evidence of microvascular and macrovascular complications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

The HLA dictionary 1999: a summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR and -DQ antigens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Nomenclature for factors of the HLA system, 1998.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0008-8749%2803%2900043-1

Release of IL-1 from mononuclear phagocytes

7 January 2021

23

1 reference

https://api.crossref.org/works/10.1016/S0008-8749(03)00043-1

HLA class II polymorphism and genetic susceptibility to insulin-dependent diabetes mellitus

1 January 2024

32

1 reference

https://api.crossref.org/works/10.1016/S0008-8749(03)00043-1

1 January 2024

Identifiers

1 reference

6 February 2018

1 reference

6 February 2018