(Q47920146)

6 February 2018

review article

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title

Interleukin-2 and systemic lupus erythematosus--fifteen years later (English)

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6 February 2018

systemic lupus erythematosus

main subject

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author name string

J C Crispin

series ordinal

1

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6 February 2018

J Alcocer-Varela

series ordinal

2

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6 February 2018

publication date

1 January 1998

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6 February 2018

published in

Lupus

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6 February 2018

volume

7

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6 February 2018

issue

4

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6 February 2018

page(s)

214-222

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6 February 2018

Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor

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Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells

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Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus

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Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene delivery

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Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene

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Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2

21 January 2018

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Decreased production of and response to interleukin-2 by cultured lymphocytes from patients with systemic lupus erythematosus

21 January 2018

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Correction of interleukin-2 production in patients with systemic lupus erythematosus by removal of spontaneously activated suppressor cells

21 January 2018

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Non-cytotoxic, IL-4, IL-5, IL-10 producing CD8+ T cells: their activation and effector functions.

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Lymphokines in autoimmunity: relationship between interleukin-2 and interferon-gamma production in systemic lupus erythematosus

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Molecular regulation of the IL-2 gene: rheostatic control of the immune system

21 January 2018

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Analysis of proteins that interact with the IL-2 regulatory region in patients with rheumatic diseases

21 January 2018

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Cytokine gene profile in circulating blood mononuclear cells from patients with systemic lupus erythematosus: increased interleukin-2 but not interleukin-4 mRNA.

21 January 2018

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Familial occurrence of impaired interleukin-2 activity and increased peripheral blood B cells actively secreting immunoglobulins in systemic lupus erythematosus

21 January 2018

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Activation markers on peripheral blood T cells from patients with active or inactive systemic lupus erythematosus. Correlation with proliferative responses and production of IL-2.

21 January 2018

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Oncogene expression in autoimmune and normal peripheral blood mononuclear cells

21 January 2018

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Interleukin-2 receptor expression in peripheral blood lymphocytes from systemic lupus erythematosus patients: relationship to clinical activity

21 January 2018

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The soluble interleukin-2 receptor: biology, function, and clinical application

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Significance of Self-Recognition and Interleukin-2 for Immunoregulation, Autoimmunity and Cancer

21 January 2018

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The cellular basis of the impaired autologous mixed lymphocyte reaction in patients with systemic lupus erythematosus

21 January 2018

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Failure of autologous mixed lymphocyte reactions between T and non-T cells in patients with systemic lupus erythematosus

21 January 2018

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Cytokine abnormalities in human lupus

21 January 2018

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Dysregulation of interleukin-10 production in relatives of patients with systemic lupus erythematosus.

21 January 2018

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Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus

21 January 2018

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Defective B7 expression on antigen-presenting cells underlying T cell activation abnormalities in systemic lupus erythematosus (SLE) patients

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Differential Effects of IL-10 on Proliferation and Cytokine Production of Human gamma/delta and alpha/beta T cells

21 January 2018

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Three-dimensional structure of interleukin-2

21 January 2018

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Induction of sensitivity to activation-induced death in primary CD4+ cells: a role for interleukin-2 in the negative regulation of responses by mature CD4+ T cells

21 January 2018

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Interleukin-2 is indispensable for development of immunological self-tolerance

21 January 2018

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In vivo administration of interleukin-2 turns on anergic self-reactive T cells and leads to autoimmune disease

21 January 2018

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Administration of anti-interleukin-2 receptor alpha antibody in vivo induces localized autoimmune disease

21 January 2018

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21 January 2018

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B cell hyperresponsiveness to interleukin 2 and the age-associated decline in murine lupus

21 January 2018

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Interleukin 2 deficiencies in rheumatoid arthritis and systemic lupus erythematosus

21 January 2018

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In vitro correction of the interleukin 2 defect of autoimmune mice

21 January 2018

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Functional T cell subpopulations responsible for hyposecretion of IL-2 in patients with systemic lupus erythematosus

21 January 2018

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Deficient phytohemagglutinin-induced interleukin-2 activity in patients with inactive systemic lupus erythematosus is correctable by the addition of phorbol myristate acetate

21 January 2018

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Impaired T-cell activation in patients with systemic lupus erythematosus

21 January 2018

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A defect in the protein kinase C system in T cells from patients with systemic lupus erythematosus

21 January 2018

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Effect of CD28 antibody on T cells from patients with systemic lupus erythematosus

21 January 2018

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The basis of autoimmunity in MRL-lpr/lpr mice: a role for self Ia-reactive T cells

21 January 2018

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Relationship of IL-2, IL-2R (CD25+), soluble IL-2R and IL-4 with disease activity in SLE patients

21 January 2018

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In vitro type-1 and type-2 cytokine production in systemic lupus erythematosus: lack of relationship with clinical disease activity

21 January 2018

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Longitudinal study on the production of and cellular response to interleukin-2 in patients with systemic lupus erythematosus

21 January 2018

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In vitro apoptosis and expression of apoptosis-related molecules in lymphocytes from patients with systemic lupus erythematosus and other autoimmune diseases

21 January 2018

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HLA-DP+ T cells and deficient interleukin-2 production in patients with systemic lupus erythematosus

21 January 2018

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Interleukin-2 deficiency, genes, and systemic lupus erythematosus

21 January 2018

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Low serum levels of dehydroepiandrosterone may cause deficient IL-2 production by lymphocytes in patients with systemic lupus erythematosus (SLE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

Decreased expression of interleukin-2 binding molecules (p70/75) in T cells from patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

Interleukin-4 regulates the interleukin-2 receptors on human peripheral blood B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

Soluble interleukin 2 receptor molecules in the serum of patients with autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

Cerebrospinal fluid soluble interleukin-2 receptor in cerebral lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

Two types of antibodies inhibiting interleukin-2 production by normal lymphocytes in patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

Interleukin 2, production in the syngeneic mixed lymphocyte reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

Abnormalities in autologous mixed lymphocyte reaction-activated immunologic processes in systemic lupus erythematosus and their possible correction by interleukin 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

Differences in the kinetics of the autologous mixed lymphocyte reaction between the various connective tissue diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

Defective antigen-presenting cell function in patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

Disease severity in patients with systemic lupus erythematosus correlates with an increased ratio of interleukin-10:interferon-gamma-secreting cells in the peripheral blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F096120398678920028

10.1191/096120398678920028

21 January 2018

Identifiers

DOI

1 reference

6 February 2018

1 reference

6 February 2018